Difference between revisions of "YMR313C"

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==Community Commentary==
 
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==References==
 
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Revision as of 08:18, 30 January 2007

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Systematic name YMR313C
Gene name TGL3
Aliases
Feature type ORF, Verified
Coordinates Chr XIII:901306..899378


Description of YMR313C: Triacylglycerol lipase of the lipid particle, responsible for all the TAG lipase activity of the lipid particle; contains the consensus sequence motif GXSXG, which is found in lipolytic enzymes[1]




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Community Commentary

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Alleles, Strains, and Phenotypes

Multiple Knockout Strains

Together with: TGL4
Phenotype(s): Loss of function (Null), Recessive, Viable

tgl3 tgl4 double mutants are unable to degrade triglycerides in lag and early log-phases of growth [2] [3]


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References

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  1. Athenstaedt K and Daum G (2003) YMR313c/TGL3 encodes a novel triacylglycerol lipase located in lipid particles of Saccharomyces cerevisiae. J Biol Chem 278(26):23317-23 SGD PMID 12682047
  2. Kurat CF, et al. (2006) Obese yeast: triglyceride lipolysis is functionally conserved from mammals to yeast. J Biol Chem 281(1):491-500 SGD PMID 16267052
  3. submitted by Sepp D. Kohlwein on 2006-05-22

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