YMR313C
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| Systematic name | YMR313C |
| Gene name | TGL3 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XIII:901307..899379 |
| Primary SGDID | S000004930 |
Description of YMR313C: Bifunctional enzyme with triacylglycerol lipase and lysophosphatidylethanolamine acyltransferase activity; responsible for all the triacylglycerol lipase activity of the lipid particle; required with Tgl4p for timely bud formation[1][2][3]
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Contents
Community Commentary
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Alleles, Strains, and Phenotypes
Multiple Knockout Strains
Together with: TGL4
Phenotype(s): Loss of function (Null), Recessive, Viable
tgl3 tgl4 double mutants are unable to degrade triglycerides in lag and early log-phases of growth [4] [5]
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References
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- ↑ Athenstaedt K and Daum G (2003) YMR313c/TGL3 encodes a novel triacylglycerol lipase located in lipid particles of Saccharomyces cerevisiae. J Biol Chem 278(26):23317-23 SGD PMID 12682047
- ↑ Kurat CF, et al. (2009) Cdk1/Cdc28-dependent activation of the major triacylglycerol lipase Tgl4 in yeast links lipolysis to cell-cycle progression. Mol Cell 33(1):53-63 SGD PMID 19150427
- ↑ Rajakumari S and Daum G (2010) Janus-faced Enzymes Yeast Tgl3p and Tgl5p Catalyze Lipase and Acyltransferase Reactions. Mol Biol Cell 21(4):501-10 SGD PMID 20016004
- ↑ Kurat CF, et al. (2006) Obese yeast: triglyceride lipolysis is functionally conserved from mammals to yeast. J Biol Chem 281(1):491-500 SGD PMID 16267052
- ↑ submitted by Sepp D. Kohlwein on 2006-05-22
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