Difference between revisions of "YMR284W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004897 YMR284W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''YKU70 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''YKU70 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr XIII: | + | |nowrap| Chr XIII:838187..839995 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004897 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004897 | ||
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| − | '''Description of YMR284W:''' Subunit of the telomeric Ku complex (Yku70p-Yku80p), involved in telomere length maintenance, structure and telomere position effect; relocates to sites of double-strand cleavage to promote nonhomologous end joining during DSB repair<ref name=' | + | '''Description of YMR284W:''' Subunit of the telomeric Ku complex (Yku70p-Yku80p), involved in telomere length maintenance, structure and telomere position effect; relocates to sites of double-strand cleavage to promote nonhomologous end joining during DSB repair<ref name='S000074970'>Bertuch AA and Lundblad V (2003) The Ku heterodimer performs separable activities at double-strand breaks and chromosome termini. Mol Cell Biol 23(22):8202-15 {{SGDpaper|S000074970}} PMID 14585978</ref><ref name='S000049359'>Boulton SJ and Jackson SP (1996) Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways. EMBO J 15(18):5093-103 {{SGDpaper|S000049359}} PMID 8890183</ref><ref name='S000047483'>Boulton SJ and Jackson SP (1998) Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing. EMBO J 17(6):1819-28 {{SGDpaper|S000047483}} PMID 9501103</ref><ref name='S000052504'>Laroche T, et al. (1998) Mutation of yeast Ku genes disrupts the subnuclear organization of telomeres. Curr Biol 8(11):653-6 {{SGDpaper|S000052504}} PMID 9635192</ref><ref name='S000044221'>Mages GJ, et al. (1996) Involvement of the Saccharomyces cerevisiae HDF1 gene in DNA double-strand break repair and recombination. J Biol Chem 271(14):7910-5 {{SGDpaper|S000044221}} PMID 8626469</ref><ref name='S000039233'>Martin SG, et al. (1999) Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast. Cell 97(5):621-33 {{SGDpaper|S000039233}} PMID 10367891</ref><ref name='S000041209'>Milne GT, et al. (1996) Mutations in two Ku homologs define a DNA end-joining repair pathway in Saccharomyces cerevisiae. Mol Cell Biol 16(8):4189-98 {{SGDpaper|S000041209}} PMID 8754818</ref><ref name='S000050484'>Porter SE, et al. (1996) The DNA-binding protein Hdf1p (a putative Ku homologue) is required for maintaining normal telomere length in Saccharomyces cerevisiae. Nucleic Acids Res 24(4):582-5 |
| − | {{SGDpaper| | + | {{SGDpaper|S000050484}} PMID 8604297</ref> |
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Latest revision as of 07:45, 23 January 2012
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| Systematic name | YMR284W |
| Gene name | YKU70 |
| Aliases | HDF1, KU70, NES24 |
| Feature type | ORF, Verified |
| Coordinates | Chr XIII:838187..839995 |
| Primary SGDID | S000004897 |
Description of YMR284W: Subunit of the telomeric Ku complex (Yku70p-Yku80p), involved in telomere length maintenance, structure and telomere position effect; relocates to sites of double-strand cleavage to promote nonhomologous end joining during DSB repair[1][2][3][4][5][6][7][8]
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References
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- ↑ Bertuch AA and Lundblad V (2003) The Ku heterodimer performs separable activities at double-strand breaks and chromosome termini. Mol Cell Biol 23(22):8202-15 SGD PMID 14585978
- ↑ Boulton SJ and Jackson SP (1996) Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways. EMBO J 15(18):5093-103 SGD PMID 8890183
- ↑ Boulton SJ and Jackson SP (1998) Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing. EMBO J 17(6):1819-28 SGD PMID 9501103
- ↑ Laroche T, et al. (1998) Mutation of yeast Ku genes disrupts the subnuclear organization of telomeres. Curr Biol 8(11):653-6 SGD PMID 9635192
- ↑ Mages GJ, et al. (1996) Involvement of the Saccharomyces cerevisiae HDF1 gene in DNA double-strand break repair and recombination. J Biol Chem 271(14):7910-5 SGD PMID 8626469
- ↑ Martin SG, et al. (1999) Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast. Cell 97(5):621-33 SGD PMID 10367891
- ↑ Milne GT, et al. (1996) Mutations in two Ku homologs define a DNA end-joining repair pathway in Saccharomyces cerevisiae. Mol Cell Biol 16(8):4189-98 SGD PMID 8754818
- ↑ Porter SE, et al. (1996) The DNA-binding protein Hdf1p (a putative Ku homologue) is required for maintaining normal telomere length in Saccharomyces cerevisiae. Nucleic Acids Res 24(4):582-5 SGD PMID 8604297
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