Difference between revisions of "YMR078C"

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=== Alleles, Strains, and Phenotypes ===
 
[[Category:Topic:Alleles, Strains, and Phenotypes]]
 
==== Complete Deletion ====
 
[[Category:Topic:Alleles, Strains, and Phenotypes:Complete Deletion]]
 
'''Phenotype(s)''': Viable [[Category:Phenotype:Viable]]
 
 
Deletion mutant is defective in telomere positioning to nuclear periphery. <ref name='S000114577'>Hiraga S, et al. (2006) The Ctf18 RFC-like complex positions yeast telomeres but does not specify their replication time. EMBO J 25(7):1505-14 {{SGDpaper|S000114577}} PMID 16525505</ref> <ref name = 'CAset6827-2006-06-20'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=6827 Shin-ichiro Hiraga] on 2006-06-20</ref>
 
 
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==Community Commentary==
 
==Community Commentary==

Revision as of 11:51, 24 January 2007

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Systematic name YMR078C
Gene name CTF18
Aliases CHL12
Feature type ORF, Verified
Coordinates Chr XIII:424727..422502
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Description of YMR078C: Subunit of a complex with Ctf8p that shares some subunits with Replication Factor C and is required for sister chromatid cohesion; may have overlapping functions with Rad24p in the DNA damage replication checkpoint[1][2]



Community Commentary

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Alleles, Strains, and Phenotypes

Complete Deletion

Phenotype(s): Viable

Deletion mutant is defective in telomere positioning to nuclear periphery. [3] [4]


References

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  1. Naiki T, et al. (2001) Chl12 (Ctf18) forms a novel replication factor C-related complex and functions redundantly with Rad24 in the DNA replication checkpoint pathway. Mol Cell Biol 21(17):5838-45 SGD PMID 11486023
  2. Mayer ML, et al. (2001) Identification of RFC(Ctf18p, Ctf8p, Dcc1p): an alternative RFC complex required for sister chromatid cohesion in S. cerevisiae. Mol Cell 7(5):959-70 SGD PMID 11389843
  3. Hiraga S, et al. (2006) The Ctf18 RFC-like complex positions yeast telomeres but does not specify their replication time. EMBO J 25(7):1505-14 SGD PMID 16525505
  4. submitted by Shin-ichiro Hiraga on 2006-06-20

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