YMR078C

From SGD-Wiki
Jump to: navigation, search

Share your knowledge...Edit this entry! <protect>

Systematic name YMR078C
Gene name CTF18
Aliases CHL12
Feature type ORF, Verified
Coordinates Chr XIII:424728..422503
Primary SGDID S000004683


Description of YMR078C: Subunit of a complex with Ctf8p that shares some subunits with Replication Factor C and is required for sister chromatid cohesion; may have overlapping functions with Rad24p in the DNA damage replication checkpoint[1][2]




</protect>

Community Commentary

About Community Commentary. Please share your knowledge!

Alleles, Strains, and Phenotypes

Complete Deletion

Phenotype(s): Viable

Deletion mutant is defective in telomere positioning to nuclear periphery. [3] [4]





<protect>

References

See Help:References on how to add references

  1. Mayer ML, et al. (2001) Identification of RFC(Ctf18p, Ctf8p, Dcc1p): an alternative RFC complex required for sister chromatid cohesion in S. cerevisiae. Mol Cell 7(5):959-70 SGD PMID 11389843
  2. Naiki T, et al. (2001) Chl12 (Ctf18) forms a novel replication factor C-related complex and functions redundantly with Rad24 in the DNA replication checkpoint pathway. Mol Cell Biol 21(17):5838-45 SGD PMID 11486023
  3. Hiraga S, et al. (2006) The Ctf18 RFC-like complex positions yeast telomeres but does not specify their replication time. EMBO J 25(7):1505-14 SGD PMID 16525505
  4. submitted by Shin-ichiro Hiraga on 2006-06-20

See Help:Categories on how to add the wiki page for this gene to a Category </protect>