Difference between revisions of "YLR398C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004390 YLR398C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''SKI2 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''SKI2 '' | ||
Latest revision as of 07:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YLR398C |
| Gene name | SKI2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:919019..915156 |
| Primary SGDID | S000004390 |
Description of YLR398C: Ski complex component and putative RNA helicase, mediates 3'-5' RNA degradation by the cytoplasmic exosome; null mutants have superkiller phenotype of increased viral dsRNAs and are synthetic lethal with mutations in 5'-3' mRNA decay[1][2][3][4]
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References
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- ↑ Anderson JS and Parker RP (1998) The 3' to 5' degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3' to 5' exonucleases of the exosome complex. EMBO J 17(5):1497-506 SGD PMID 9482746
- ↑ Brown JT, et al. (2000) The yeast antiviral proteins Ski2p, Ski3p, and Ski8p exist as a complex in vivo. RNA 6(3):449-57 SGD PMID 10744028
- ↑ Toh-E A, et al. (1978) Chromosomal superkiller mutants of Saccharomyces cerevisiae. J Bacteriol 136(3):1002-7 SGD PMID 363683
- ↑ Widner WR and Wickner RB (1993) Evidence that the SKI antiviral system of Saccharomyces cerevisiae acts by blocking expression of viral mRNA. Mol Cell Biol 13(7):4331-41 SGD PMID 8321235
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