Difference between revisions of "YLR320W"
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| − | '''Description of YLR320W:''' | + | '''Description of YLR320W:''' Subunit of an E3 ubiquitin ligase complex involved in replication repair; stabilizes protein components of the replication fork, such as the fork-pausing complex and leading strand polymerase, preventing fork collapse and promoting efficient recovery during replication stress; required for accurate meiotic chromosome segregation<ref name='S000073328'>Araki Y, et al. (2003) Budding yeast mcm10/dna43 mutant requires a novel repair pathway for viability. Genes Cells 8(5):465-80 {{SGDpaper|S000073328}} PMID 12694535</ref><ref name='S000069458'>Bennett CB, et al. (2001) Genes required for ionizing radiation resistance in yeast. Nat Genet 29(4):426-34 {{SGDpaper|S000069458}} PMID 11726929</ref><ref name='S000125772'>Duro E, et al. (2008) Budding yeast Mms22 and Mms1 regulate homologous recombination induced by replisome blockage. DNA Repair (Amst) 7(5):811-8 {{SGDpaper|S000125772}} PMID 18321796</ref><ref name='S000124986'>Jordan PW, et al. (2007) Novel roles for selected genes in meiotic DNA processing. PLoS Genet 3(12):e222 {{SGDpaper|S000124986}} PMID 18069899</ref><ref name='S000147764'>Vaisica JA, et al. (2011) Mms1 and Mms22 stabilize the replisome during replication stress. Mol Biol Cell 22(13):2396-408 |
| − | {{SGDpaper| | + | {{SGDpaper|S000147764}} PMID 21593207</ref> |
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Latest revision as of 14:05, 9 March 2012
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| Systematic name | YLR320W |
| Gene name | MMS22 |
| Aliases | SLM2 |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:771940..776304 |
| Primary SGDID | S000004312 |
Description of YLR320W: Subunit of an E3 ubiquitin ligase complex involved in replication repair; stabilizes protein components of the replication fork, such as the fork-pausing complex and leading strand polymerase, preventing fork collapse and promoting efficient recovery during replication stress; required for accurate meiotic chromosome segregation[1][2][3][4][5]
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References
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- ↑ Araki Y, et al. (2003) Budding yeast mcm10/dna43 mutant requires a novel repair pathway for viability. Genes Cells 8(5):465-80 SGD PMID 12694535
- ↑ Bennett CB, et al. (2001) Genes required for ionizing radiation resistance in yeast. Nat Genet 29(4):426-34 SGD PMID 11726929
- ↑ Duro E, et al. (2008) Budding yeast Mms22 and Mms1 regulate homologous recombination induced by replisome blockage. DNA Repair (Amst) 7(5):811-8 SGD PMID 18321796
- ↑ Jordan PW, et al. (2007) Novel roles for selected genes in meiotic DNA processing. PLoS Genet 3(12):e222 SGD PMID 18069899
- ↑ Vaisica JA, et al. (2011) Mms1 and Mms22 stabilize the replisome during replication stress. Mol Biol Cell 22(13):2396-408 SGD PMID 21593207
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