YLR045C
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| Systematic name | YLR045C |
| Gene name | STU2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:237704..235038 |
Description of YLR045C: Microtubule-associated protein (MAP) of the XMAP215/Dis1 family; regulates microtubule dynamics during spindle orientation and metaphase chromosome alignment; interacts with spindle pole body component Spc72p[1][2][3][4]
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [5] [6]
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References
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- ↑ Kosco KA, et al. (2001) Control of microtubule dynamics by Stu2p is essential for spindle orientation and metaphase chromosome alignment in yeast. Mol Biol Cell 12(9):2870-80 SGD PMID 11553724
- ↑ Severin F, et al. (2001) Stu2 promotes mitotic spindle elongation in anaphase. J Cell Biol 153(2):435-42 SGD PMID 11309422
- ↑ Wang PJ and Huffaker TC (1997) Stu2p: A microtubule-binding protein that is an essential component of the yeast spindle pole body. J Cell Biol 139(5):1271-80 SGD PMID 9382872
- ↑ Chen XP, et al. (1998) The yeast spindle pole body component Spc72p interacts with Stu2p and is required for proper microtubule assembly. J Cell Biol 141(5):1169-79 SGD PMID 9606209
- ↑ Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ submitted by Jeff Ubersax on 2004-01-29
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