YLR045C

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Systematic name YLR045C
Gene name STU2
Aliases
Feature type ORF, Verified
Coordinates Chr XII:237703..235037
Primary SGDID S000004035


Description of YLR045C: Microtubule-associated protein (MAP) of the XMAP215/Dis1 family; regulates microtubule dynamics during spindle orientation and metaphase chromosome alignment; interacts with spindle pole body component Spc72p[1][2][3][4]




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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [5] [6]





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References

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  1. Jump up Chen XP, et al. (1998) The yeast spindle pole body component Spc72p interacts with Stu2p and is required for proper microtubule assembly. J Cell Biol 141(5):1169-79 SGD PMID 9606209
  2. Jump up Kosco KA, et al. (2001) Control of microtubule dynamics by Stu2p is essential for spindle orientation and metaphase chromosome alignment in yeast. Mol Biol Cell 12(9):2870-80 SGD PMID 11553724
  3. Jump up Severin F, et al. (2001) Stu2 promotes mitotic spindle elongation in anaphase. J Cell Biol 153(2):435-42 SGD PMID 11309422
  4. Jump up Wang PJ and Huffaker TC (1997) Stu2p: A microtubule-binding protein that is an essential component of the yeast spindle pole body. J Cell Biol 139(5):1271-80 SGD PMID 9382872
  5. Jump up Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  6. Jump up submitted by Jeff Ubersax on 2004-01-29

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