Difference between revisions of "YLR045C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004035 YLR045C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004035 YLR045C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''STU2 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''STU2 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XII:237704..235038
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|nowrap| Chr XII:237703..235037
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000004035
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000004035
 
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'''Description of YLR045C:''' Microtubule-associated protein (MAP) of the XMAP215/Dis1 family; regulates microtubule dynamics during spindle orientation and metaphase chromosome alignment; interacts with spindle pole body component Spc72p<ref name='S000044510'>Chen XP, et al. (1998) The yeast spindle pole body component Spc72p interacts with Stu2p and is required for proper microtubule assembly. J Cell Biol 141(5):1169-79 {{SGDpaper|S000044510}} PMID 9606209</ref><ref name='S000051489'>Wang PJ and Huffaker TC (1997) Stu2p: A microtubule-binding protein that is an essential component of the yeast spindle pole body. J Cell Biol 139(5):1271-80 {{SGDpaper|S000051489}} PMID 9382872</ref><ref name='S000060134'>Severin F, et al. (2001) Stu2 promotes mitotic spindle elongation in anaphase. J Cell Biol 153(2):435-42 {{SGDpaper|S000060134}} PMID 11309422</ref><ref name='S000068994'>Kosco KA, et al. (2001) Control of microtubule dynamics by Stu2p is essential for spindle orientation and metaphase chromosome alignment in yeast. Mol Biol Cell 12(9):2870-80
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'''Description of YLR045C:''' Microtubule-associated protein (MAP) of the XMAP215/Dis1 family; regulates microtubule dynamics during spindle orientation and metaphase chromosome alignment; interacts with spindle pole body component Spc72p<ref name='S000044510'>Chen XP, et al. (1998) The yeast spindle pole body component Spc72p interacts with Stu2p and is required for proper microtubule assembly. J Cell Biol 141(5):1169-79 {{SGDpaper|S000044510}} PMID 9606209</ref><ref name='S000068994'>Kosco KA, et al. (2001) Control of microtubule dynamics by Stu2p is essential for spindle orientation and metaphase chromosome alignment in yeast. Mol Biol Cell 12(9):2870-80 {{SGDpaper|S000068994}} PMID 11553724</ref><ref name='S000060134'>Severin F, et al. (2001) Stu2 promotes mitotic spindle elongation in anaphase. J Cell Biol 153(2):435-42 {{SGDpaper|S000060134}} PMID 11309422</ref><ref name='S000051489'>Wang PJ and Huffaker TC (1997) Stu2p: A microtubule-binding protein that is an essential component of the yeast spindle pole body. J Cell Biol 139(5):1271-80
  {{SGDpaper|S000068994}} PMID 11553724</ref>
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  {{SGDpaper|S000051489}} PMID 9382872</ref>
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YLR045C
Gene name STU2
Aliases
Feature type ORF, Verified
Coordinates Chr XII:237703..235037
Primary SGDID S000004035


Description of YLR045C: Microtubule-associated protein (MAP) of the XMAP215/Dis1 family; regulates microtubule dynamics during spindle orientation and metaphase chromosome alignment; interacts with spindle pole body component Spc72p[1][2][3][4]




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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [5] [6]





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References

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  1. Chen XP, et al. (1998) The yeast spindle pole body component Spc72p interacts with Stu2p and is required for proper microtubule assembly. J Cell Biol 141(5):1169-79 SGD PMID 9606209
  2. Kosco KA, et al. (2001) Control of microtubule dynamics by Stu2p is essential for spindle orientation and metaphase chromosome alignment in yeast. Mol Biol Cell 12(9):2870-80 SGD PMID 11553724
  3. Severin F, et al. (2001) Stu2 promotes mitotic spindle elongation in anaphase. J Cell Biol 153(2):435-42 SGD PMID 11309422
  4. Wang PJ and Huffaker TC (1997) Stu2p: A microtubule-binding protein that is an essential component of the yeast spindle pole body. J Cell Biol 139(5):1271-80 SGD PMID 9382872
  5. Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  6. submitted by Jeff Ubersax on 2004-01-29

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