YLL040C
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| Systematic name | YLL040C |
| Gene name | VPS13 |
| Aliases | SOI1, VPT2 |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:63644..54210 |
Description of YLL040C: Protein of unknown function; heterooligomeric or homooligomeric complex; peripherally associated with membranes; homologous to human COH1; involved in sporulation, vacuolar protein sorting and protein-Golgi retention[1][2]
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Protein Details
Protein Localization
Vps13p acts in a positive way on TLS1 retrieval from the PVC to the TGN [1] [3]
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References
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- ↑ 1.0 1.1 Brickner JH and Fuller RS (1997) SOI1 encodes a novel, conserved protein that promotes TGN-endosomal cycling of Kex2p and other membrane proteins by modulating the function of two TGN localization signals. J Cell Biol 139(1):23-36 SGD PMID 9314526
- ↑ Redding K, et al. (1996) Allele-specific suppression of a defective trans-Golgi network (TGN) localization signal in Kex2p identifies three genes involved in localization of TGN transmembrane proteins. Mol Cell Biol 16(11):6208-17 SGD PMID 8887651
- ↑ submitted by EJ Brace on 2003-08-13
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