Difference between revisions of "YLL021W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003944 YLL021W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003944 YLL021W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SPA2 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SPA2 ''

Latest revision as of 07:45, 23 January 2012

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Systematic name YLL021W
Gene name SPA2
Aliases FUS6, PEA1
Feature type ORF, Verified
Coordinates Chr XII:100947..105347
Primary SGDID S000003944


Description of YLL021W: Component of the polarisome, which functions in actin cytoskeletal organization during polarized growth; acts as a scaffold for Mkk1p and Mpk1p cell wall integrity signaling components; potential Cdc28p substrate[1][2][3]




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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [2] [4]





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References

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  1. Sheu YJ, et al. (1998) Spa2p interacts with cell polarity proteins and signaling components involved in yeast cell morphogenesis. Mol Cell Biol 18(7):4053-69 SGD PMID 9632790
  2. 2.0 2.1 Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  3. van Drogen F and Peter M (2002) Spa2p functions as a scaffold-like protein to recruit the Mpk1p MAP kinase module to sites of polarized growth. Curr Biol 12(19):1698-703 SGD PMID 12361575
  4. submitted by Jeff Ubersax on 2004-01-29

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