YLL021W
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| Systematic name | YLL021W |
| Gene name | SPA2 |
| Aliases | FUS6, PEA1 |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:100947..105347 |
| Primary SGDID | S000003944 |
Description of YLL021W: Component of the polarisome, which functions in actin cytoskeletal organization during polarized growth; acts as a scaffold for Mkk1p and Mpk1p cell wall integrity signaling components; potential Cdc28p substrate[1][2][3]
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [2] [4]
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References
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- Jump up ↑ Sheu YJ, et al. (1998) Spa2p interacts with cell polarity proteins and signaling components involved in yeast cell morphogenesis. Mol Cell Biol 18(7):4053-69 SGD PMID 9632790
- ↑ Jump up to: 2.0 2.1 Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- Jump up ↑ van Drogen F and Peter M (2002) Spa2p functions as a scaffold-like protein to recruit the Mpk1p MAP kinase module to sites of polarized growth. Curr Biol 12(19):1698-703 SGD PMID 12361575
- Jump up ↑ submitted by Jeff Ubersax on 2004-01-29
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