Difference between revisions of "YKR082W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001790 YKR082W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''NUP133 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''NUP133 '' | ||
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| − | '''Description of YKR082W:''' Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC); | + | '''Description of YKR082W:''' Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC); contributes to nucleocytoplasmic transport and NPC biogenesis and is involved in establishment of a normal nucleocytoplasmic concentration gradient of the GTPase Gsp1p; also plays roles in several processes that may require localization of genes or chromosomes at the nuclear periphery, including double-strand break repair, transcription and chromatin silencing; homologous to human NUP133<ref name='S000074016'>Allen NP, et al. (2002) Deciphering networks of protein interactions at the nuclear pore complex. Mol Cell Proteomics 1(12):930-46 {{SGDpaper|S000074016}} PMID 12543930</ref><ref name='S000135178'>Fernandez-Martinez J and Rout MP (2009) Nuclear pore complex biogenesis. Curr Opin Cell Biol 21(4):603-12 {{SGDpaper|S000135178}} PMID 19524430</ref><ref name='S000148381'>Fernandez-Martinez J, et al. (2012) Structure-function mapping of a heptameric module in the nuclear pore complex. J Cell Biol () {{SGDpaper|S000148381}} PMID 22331846</ref><ref name='S000068846'>Gao H, et al. (2003) Nuclear accumulation of the small GTPase Gsp1p depends on nucleoporins Nup133p, Rat2p/Nup120p, Nup85p, Nic96p, and the acetyl-CoA carboxylase Acc1p. J Biol Chem 278(28):25331-40 {{SGDpaper|S000068846}} PMID 12730220</ref><ref name='S000131804'>Lutzmann M, et al. (2002) Modular self-assembly of a Y-shaped multiprotein complex from seven nucleoporins. EMBO J 21(3):387-97 {{SGDpaper|S000131804}} PMID 11823431</ref><ref name='S000056415'>Rout MP, et al. (2000) The yeast nuclear pore complex: composition, architecture, and transport mechanism. J Cell Biol 148(4):635-51 {{SGDpaper|S000056415}} PMID 10684247</ref><ref name='S000147513'>Sarma NJ, et al. (2011) The nuclear pore complex mediates binding of the mig1 repressor to target promoters. PLoS One 6(11):e27117 {{SGDpaper|S000147513}} PMID 22110603</ref><ref name='S000114163'>Therizols P, et al. (2006) Telomere tethering at the nuclear periphery is essential for efficient DNA double strand break repair in subtelomeric region. J Cell Biol 172(2):189-99 {{SGDpaper|S000114163}} PMID 16418532</ref><ref name='S000146226'>Tous C, et al. (2011) A novel assay identifies transcript elongation roles for the Nup84 complex and RNA processing factors. EMBO J 30(10):1953-64 |
{{SGDpaper|S000146226}} PMID 21478823</ref> | {{SGDpaper|S000146226}} PMID 21478823</ref> | ||
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Latest revision as of 14:05, 11 June 2012
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| Systematic name | YKR082W |
| Gene name | NUP133 |
| Aliases | RAT3 |
| Feature type | ORF, Verified |
| Coordinates | Chr XI:592825..596298 |
| Primary SGDID | S000001790 |
Description of YKR082W: Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC); contributes to nucleocytoplasmic transport and NPC biogenesis and is involved in establishment of a normal nucleocytoplasmic concentration gradient of the GTPase Gsp1p; also plays roles in several processes that may require localization of genes or chromosomes at the nuclear periphery, including double-strand break repair, transcription and chromatin silencing; homologous to human NUP133[1][2][3][4][5][6][7][8][9]
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References
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- ↑ Allen NP, et al. (2002) Deciphering networks of protein interactions at the nuclear pore complex. Mol Cell Proteomics 1(12):930-46 SGD PMID 12543930
- ↑ Fernandez-Martinez J and Rout MP (2009) Nuclear pore complex biogenesis. Curr Opin Cell Biol 21(4):603-12 SGD PMID 19524430
- ↑ Fernandez-Martinez J, et al. (2012) Structure-function mapping of a heptameric module in the nuclear pore complex. J Cell Biol () SGD PMID 22331846
- ↑ Gao H, et al. (2003) Nuclear accumulation of the small GTPase Gsp1p depends on nucleoporins Nup133p, Rat2p/Nup120p, Nup85p, Nic96p, and the acetyl-CoA carboxylase Acc1p. J Biol Chem 278(28):25331-40 SGD PMID 12730220
- ↑ Lutzmann M, et al. (2002) Modular self-assembly of a Y-shaped multiprotein complex from seven nucleoporins. EMBO J 21(3):387-97 SGD PMID 11823431
- ↑ Rout MP, et al. (2000) The yeast nuclear pore complex: composition, architecture, and transport mechanism. J Cell Biol 148(4):635-51 SGD PMID 10684247
- ↑ Sarma NJ, et al. (2011) The nuclear pore complex mediates binding of the mig1 repressor to target promoters. PLoS One 6(11):e27117 SGD PMID 22110603
- ↑ Therizols P, et al. (2006) Telomere tethering at the nuclear periphery is essential for efficient DNA double strand break repair in subtelomeric region. J Cell Biol 172(2):189-99 SGD PMID 16418532
- ↑ Tous C, et al. (2011) A novel assay identifies transcript elongation roles for the Nup84 complex and RNA processing factors. EMBO J 30(10):1953-64 SGD PMID 21478823
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