YKL049C

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Systematic name YKL049C
Gene name CSE4
Aliases CSL2
Feature type ORF, Verified
Coordinates Chr XI:346408..345719


Description of YKL049C: Centromere protein that resembles histones, required for proper kinetochore function; homolog of human CENP-A[1]




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Community Commentary

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Interactions

Physical

Physical interaction with NNF1
Cse4p immunoprecipitates with Nnf1p. [2] [3]


Physical interaction with MTW1
Cse4p co-immunoprecipitates with Mtw1p. [2] [3]


Physical interaction with DSN1
Cse4p co-immunopreciptates with Dsn1p. [2] [3]


Physical interaction with MIF2
Cse4p immunoprecipitates with Mif2p. [2] [3]


Physical interaction with NSL1
Cse4p immunoprecipitates with Nsl1p. [2] [3]


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References

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  1. Meluh PB, et al. (1998) Cse4p is a component of the core centromere of Saccharomyces cerevisiae. Cell 94(5):607-13 SGD PMID 9741625
  2. 2.0 2.1 2.2 2.3 2.4 Pinsky BA, et al. (2003) An Mtw1 complex promotes kinetochore biorientation that is monitored by the Ipl1/Aurora protein kinase. Dev Cell 5(5):735-45 SGD PMID 14602074
  3. 3.0 3.1 3.2 3.3 3.4 submitted by Benjamin Pinsky on 2004-03-04

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