Difference between revisions of "YKL010C"
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| − | '''Description of YKL010C:''' Ubiquitin-protein ligase (E3) that interacts with Rpt4p and Rpt6p, two subunits of the 19S particle of the 26S proteasome; cytoplasmic E3 involved in the degradation of ubiquitin fusion proteins<ref name='S000047686'>Xie Y and Varshavsky A (2000) Physical association of ubiquitin ligases and the 26S proteasome. Proc Natl Acad Sci U S A 97(6):2497-502 {{SGDpaper|S000047686}} PMID 10688918 | + | '''Description of YKL010C:''' Ubiquitin-protein ligase (E3) that interacts with Rpt4p and Rpt6p, two subunits of the 19S particle of the 26S proteasome; cytoplasmic E3 involved in the degradation of ubiquitin fusion proteins<ref name='S000058010'>Hochstrasser M (1996) Ubiquitin-dependent protein degradation. Annu Rev Genet 30:405-39 {{SGDpaper|S000058010}} PMID 8982460</ref><ref name='S000047686'>Xie Y and Varshavsky A (2000) Physical association of ubiquitin ligases and the 26S proteasome. Proc Natl Acad Sci U S A 97(6):2497-502 {{SGDpaper|S000047686}} PMID 10688918</ref><ref name='S000072012'>Xie Y and Varshavsky A (2002) UFD4 lacking the proteasome-binding region catalyses ubiquitination but is impaired in proteolysis. Nat Cell Biol 4(12):1003-7 |
{{SGDpaper|S000072012}} PMID 12447385</ref> | {{SGDpaper|S000072012}} PMID 12447385</ref> | ||
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Revision as of 14:05, 25 February 2010
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| Systematic name | YKL010C |
| Gene name | UFD4 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XI:425518..421067 |
| Primary SGDID | S000001493 |
Description of YKL010C: Ubiquitin-protein ligase (E3) that interacts with Rpt4p and Rpt6p, two subunits of the 19S particle of the 26S proteasome; cytoplasmic E3 involved in the degradation of ubiquitin fusion proteins[1][2][3]
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References
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- ↑ Hochstrasser M (1996) Ubiquitin-dependent protein degradation. Annu Rev Genet 30:405-39 SGD PMID 8982460
- ↑ Xie Y and Varshavsky A (2000) Physical association of ubiquitin ligases and the 26S proteasome. Proc Natl Acad Sci U S A 97(6):2497-502 SGD PMID 10688918
- ↑ Xie Y and Varshavsky A (2002) UFD4 lacking the proteasome-binding region catalyses ubiquitination but is impaired in proteolysis. Nat Cell Biol 4(12):1003-7 SGD PMID 12447385
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