Difference between revisions of "YKL002W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001485 YKL002W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001485 YKL002W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''DID4 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''DID4 ''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||''CHM2, GRD7, REN1, VPL2, VPS2, VPT14''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||''CHM2, GRD7, REN1, VPL2, VPS14, VPS2, VPT14''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XI:437421..438187
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|nowrap| Chr XI:437778..438544
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000001485
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000001485
 
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'''Description of YKL002W:''' Class E Vps protein of the ESCRT-III complex, required for sorting of integral membrane proteins into lumenal vesicles of multivesicular bodies, and for delivery of newly synthesized vacuolar enzymes to the vacuole, involved in endocytosis<ref name='S000073168'>Odorizzi G, et al. (2003) Bro1 is an endosome-associated protein that functions in the MVB pathway in Saccharomyces cerevisiae. J Cell Sci 116(Pt 10):1893-903 {{SGDpaper|S000073168}} PMID 12668726</ref><ref name='S000071351'>Babst M, et al. (2002) Escrt-III: an endosome-associated heterooligomeric protein complex required for mvb sorting. Dev Cell 3(2):271-82 {{SGDpaper|S000071351}} PMID 12194857</ref><ref name='S000059113'>Amerik AY, et al. (2000) The Doa4 deubiquitinating enzyme is functionally linked to the vacuolar protein-sorting and endocytic pathways. Mol Biol Cell 11(10):3365-80 {{SGDpaper|S000059113}} PMID 11029042</ref><ref name='S000040169'>Davis NG, et al. (1993) Cis- and trans-acting functions required for endocytosis of the yeast pheromone receptors. J Cell Biol 122(1):53-65
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'''Description of YKL002W:''' Class E Vps protein of the ESCRT-III complex, required for sorting of integral membrane proteins into lumenal vesicles of multivesicular bodies, and for delivery of newly synthesized vacuolar enzymes to the vacuole, involved in endocytosis<ref name='S000059113'>Amerik AY, et al. (2000) The Doa4 deubiquitinating enzyme is functionally linked to the vacuolar protein-sorting and endocytic pathways. Mol Biol Cell 11(10):3365-80 {{SGDpaper|S000059113}} PMID 11029042</ref><ref name='S000071351'>Babst M, et al. (2002) Escrt-III: an endosome-associated heterooligomeric protein complex required for mvb sorting. Dev Cell 3(2):271-82 {{SGDpaper|S000071351}} PMID 12194857</ref><ref name='S000040169'>Davis NG, et al. (1993) Cis- and trans-acting functions required for endocytosis of the yeast pheromone receptors. J Cell Biol 122(1):53-65 {{SGDpaper|S000040169}} PMID 8391002</ref><ref name='S000073168'>Odorizzi G, et al. (2003) Bro1 is an endosome-associated protein that functions in the MVB pathway in Saccharomyces cerevisiae. J Cell Sci 116(Pt 10):1893-903
  {{SGDpaper|S000040169}} PMID 8391002</ref>
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  {{SGDpaper|S000073168}} PMID 12668726</ref>
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YKL002W
Gene name DID4
Aliases CHM2, GRD7, REN1, VPL2, VPS14, VPS2, VPT14
Feature type ORF, Verified
Coordinates Chr XI:437778..438544
Primary SGDID S000001485


Description of YKL002W: Class E Vps protein of the ESCRT-III complex, required for sorting of integral membrane proteins into lumenal vesicles of multivesicular bodies, and for delivery of newly synthesized vacuolar enzymes to the vacuole, involved in endocytosis[1][2][3][4]




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References

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  1. Amerik AY, et al. (2000) The Doa4 deubiquitinating enzyme is functionally linked to the vacuolar protein-sorting and endocytic pathways. Mol Biol Cell 11(10):3365-80 SGD PMID 11029042
  2. Babst M, et al. (2002) Escrt-III: an endosome-associated heterooligomeric protein complex required for mvb sorting. Dev Cell 3(2):271-82 SGD PMID 12194857
  3. Davis NG, et al. (1993) Cis- and trans-acting functions required for endocytosis of the yeast pheromone receptors. J Cell Biol 122(1):53-65 SGD PMID 8391002
  4. Odorizzi G, et al. (2003) Bro1 is an endosome-associated protein that functions in the MVB pathway in Saccharomyces cerevisiae. J Cell Sci 116(Pt 10):1893-903 SGD PMID 12668726

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