YJR089W

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Systematic name YJR089W
Gene name BIR1
Aliases
Feature type ORF, Verified
Coordinates Chr X:587711..590575


Description of YJR089W: Essential chromosomal passenger protein involved in coordinating cell cycle events for proper chromosome segregation; C-terminal region binds Sli15p, and the middle region, upon phosphorylation, localizes Cbf2p to the spindle at anaphase[1][2][3]




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References

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  1. Widlund PO, et al. (2006) Phosphorylation of the chromosomal passenger protein Bir1 is required for localization of Ndc10 to the spindle during anaphase and full spindle elongation. Mol Biol Cell 17(3):1065-74 SGD PMID 16381814
  2. Li F, et al. (2000) Cell division regulation by BIR1, a member of the inhibitor of apoptosis family in yeast. J Biol Chem 275(10):6707-11 SGD PMID 10702224
  3. Yoon HJ and Carbon J (1999) Participation of Bir1p, a member of the inhibitor of apoptosis family, in yeast chromosome segregation events. Proc Natl Acad Sci U S A 96(23):13208-13 SGD PMID 10557299

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