YJR089W
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| Systematic name | YJR089W |
| Gene name | BIR1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr X:587710..590574 |
| Primary SGDID | S000003849 |
Description of YJR089W: Subunit of the chromosomal passenger complex (CPC; Ipl1p-Sli15p-Bir1p-Nbl1p), which regulates chromosome segregation; binds Sli15p; upon phosphorylation, localizes Cbf2p to the spindle at anaphase; inhibits apoptosis[1][2][3][4][5]
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References
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- ↑ Yoon HJ and Carbon J (1999) Participation of Bir1p, a member of the inhibitor of apoptosis family, in yeast chromosome segregation events. Proc Natl Acad Sci U S A 96(23):13208-13 SGD PMID 10557299
- ↑ Li F, et al. (2000) Cell division regulation by BIR1, a member of the inhibitor of apoptosis family in yeast. J Biol Chem 275(10):6707-11 SGD PMID 10702224
- ↑ Walter D, et al. (2006) The inhibitor-of-apoptosis protein Bir1p protects against apoptosis in S. cerevisiae and is a substrate for the yeast homologue of Omi/HtrA2. J Cell Sci 119(Pt 9):1843-51 SGD PMID 16608876
- ↑ Widlund PO, et al. (2006) Phosphorylation of the chromosomal passenger protein Bir1 is required for localization of Ndc10 to the spindle during anaphase and full spindle elongation. Mol Biol Cell 17(3):1065-74 SGD PMID 16381814
- ↑ Nakajima Y, et al. (2009) Nbl1p: a Borealin/Dasra/CSC-1-like protein essential for Aurora/Ipl1 complex function and integrity in Saccharomyces cerevisiae. Mol Biol Cell 20(6):1772-84 SGD PMID 19158380
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