Difference between revisions of "YJR089W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YJR089W YJR089W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003849 YJR089W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''BIR1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''BIR1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr X:587711..590575
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|nowrap| Chr X:587718..590582
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003849
 
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'''Description of {{PAGENAME}}:''' Essential chromosomal passenger protein involved in coordinating cell cycle events for proper chromosome segregation; C-terminal region binds Sli15p, and the middle region, upon phosphorylation, localizes Cbf2p to the spindle at anaphase<ref name='S000113988'>Widlund PO, et al. (2006) Phosphorylation of the chromosomal passenger protein Bir1 is required for localization of Ndc10 to the spindle during anaphase and full spindle elongation. Mol Biol Cell 17(3):1065-74 {{SGDpaper|S000113988}} PMID 16381814</ref><ref name='S000047232'>Li F, et al. (2000) Cell division regulation by BIR1, a member of the inhibitor of apoptosis family in yeast. J Biol Chem 275(10):6707-11 {{SGDpaper|S000047232}} PMID 10702224</ref><ref name='S000044012'>Yoon HJ and Carbon J (1999) Participation of Bir1p, a member of the inhibitor of apoptosis family, in yeast chromosome segregation events. Proc Natl Acad Sci U S A 96(23):13208-13
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'''Description of YJR089W:''' Subunit of chromosomal passenger complex (CPC; Ipl1p-Sli15p-Bir1p-Nbl1p), which regulates chromosome segregation; required for chromosome bi-orientation and for spindle assembly checkpoint activation upon reduced sister kinetochore tension<ref name='S000047232'>Li F, et al. (2000) Cell division regulation by BIR1, a member of the inhibitor of apoptosis family in yeast. J Biol Chem 275(10):6707-11 {{SGDpaper|S000047232}} PMID 10702224</ref><ref name='S000130677'>Makrantoni V and Stark MJ (2009) Efficient chromosome biorientation and the tension checkpoint in Saccharomyces cerevisiae both require Bir1. Mol Cell Biol 29(16):4552-62 {{SGDpaper|S000130677}} PMID 19528231</ref><ref name='S000129008'>Nakajima Y, et al. (2009) Nbl1p: a Borealin/Dasra/CSC-1-like protein essential for Aurora/Ipl1 complex function and integrity in Saccharomyces cerevisiae. Mol Biol Cell 20(6):1772-84 {{SGDpaper|S000129008}} PMID 19158380</ref><ref name='S000044012'>Yoon HJ and Carbon J (1999) Participation of Bir1p, a member of the inhibitor of apoptosis family, in yeast chromosome segregation events. Proc Natl Acad Sci U S A 96(23):13208-13
 
  {{SGDpaper|S000044012}} PMID 10557299</ref>
 
  {{SGDpaper|S000044012}} PMID 10557299</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YJR089W
Gene name BIR1
Aliases
Feature type ORF, Verified
Coordinates Chr X:587718..590582
Primary SGDID S000003849


Description of YJR089W: Subunit of chromosomal passenger complex (CPC; Ipl1p-Sli15p-Bir1p-Nbl1p), which regulates chromosome segregation; required for chromosome bi-orientation and for spindle assembly checkpoint activation upon reduced sister kinetochore tension[1][2][3][4]




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References

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  1. Li F, et al. (2000) Cell division regulation by BIR1, a member of the inhibitor of apoptosis family in yeast. J Biol Chem 275(10):6707-11 SGD PMID 10702224
  2. Makrantoni V and Stark MJ (2009) Efficient chromosome biorientation and the tension checkpoint in Saccharomyces cerevisiae both require Bir1. Mol Cell Biol 29(16):4552-62 SGD PMID 19528231
  3. Nakajima Y, et al. (2009) Nbl1p: a Borealin/Dasra/CSC-1-like protein essential for Aurora/Ipl1 complex function and integrity in Saccharomyces cerevisiae. Mol Biol Cell 20(6):1772-84 SGD PMID 19158380
  4. Yoon HJ and Carbon J (1999) Participation of Bir1p, a member of the inhibitor of apoptosis family, in yeast chromosome segregation events. Proc Natl Acad Sci U S A 96(23):13208-13 SGD PMID 10557299

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