Difference between revisions of "YJR089W"

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'''Description of YJR089W:''' Subunit of the chromosomal passenger complex (CPC; Ipl1p-Sli15p-Bir1p-Nbl1p), which regulates chromosome segregation; binds Sli15p; upon phosphorylation, localizes Cbf2p to the spindle at anaphase; inhibits apoptosis<ref name='S000044012'>Yoon HJ and Carbon J (1999) Participation of Bir1p, a member of the inhibitor of apoptosis family, in yeast chromosome segregation events. Proc Natl Acad Sci U S A 96(23):13208-13 {{SGDpaper|S000044012}} PMID 10557299</ref><ref name='S000047232'>Li F, et al. (2000) Cell division regulation by BIR1, a member of the inhibitor of apoptosis family in yeast. J Biol Chem 275(10):6707-11 {{SGDpaper|S000047232}} PMID 10702224</ref><ref name='S000114909'>Walter D, et al. (2006) The inhibitor-of-apoptosis protein Bir1p protects against apoptosis in S. cerevisiae and is a substrate for the yeast homologue of Omi/HtrA2. J Cell Sci 119(Pt 9):1843-51 {{SGDpaper|S000114909}} PMID 16608876</ref><ref name='S000113988'>Widlund PO, et al. (2006) Phosphorylation of the chromosomal passenger protein Bir1 is required for localization of Ndc10 to the spindle during anaphase and full spindle elongation. Mol Biol Cell 17(3):1065-74 {{SGDpaper|S000113988}} PMID 16381814</ref><ref name='S000129008'>Nakajima Y, et al. (2009) Nbl1p: a Borealin/Dasra/CSC-1-like protein essential for Aurora/Ipl1 complex function and integrity in Saccharomyces cerevisiae. Mol Biol Cell 20(6):1772-84
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'''Description of YJR089W:''' Subunit of chromosomal passenger complex (CPC; Ipl1p-Sli15p-Bir1p-Nbl1p), which regulates chromosome segregation; required for chromosome bi-orientation and for spindle assembly checkpoint activation upon reduced sister kinetochore tension<ref name='S000044012'>Yoon HJ and Carbon J (1999) Participation of Bir1p, a member of the inhibitor of apoptosis family, in yeast chromosome segregation events. Proc Natl Acad Sci U S A 96(23):13208-13 {{SGDpaper|S000044012}} PMID 10557299</ref><ref name='S000047232'>Li F, et al. (2000) Cell division regulation by BIR1, a member of the inhibitor of apoptosis family in yeast. J Biol Chem 275(10):6707-11 {{SGDpaper|S000047232}} PMID 10702224</ref><ref name='S000130677'>Makrantoni V and Stark MJ (2009) Efficient chromosome bi-orientation and the tension checkpoint in Saccharomyces cerevisiae both require Bir1. Mol Cell Biol {{SGDpaper|S000130677}} PMID 19528231</ref><ref name='S000129008'>Nakajima Y, et al. (2009) Nbl1p: a Borealin/Dasra/CSC-1-like protein essential for Aurora/Ipl1 complex function and integrity in Saccharomyces cerevisiae. Mol Biol Cell 20(6):1772-84
 
  {{SGDpaper|S000129008}} PMID 19158380</ref>
 
  {{SGDpaper|S000129008}} PMID 19158380</ref>
 
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Revision as of 14:05, 23 June 2009

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Systematic name YJR089W
Gene name BIR1
Aliases
Feature type ORF, Verified
Coordinates Chr X:587710..590574
Primary SGDID S000003849


Description of YJR089W: Subunit of chromosomal passenger complex (CPC; Ipl1p-Sli15p-Bir1p-Nbl1p), which regulates chromosome segregation; required for chromosome bi-orientation and for spindle assembly checkpoint activation upon reduced sister kinetochore tension[1][2][3][4]




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References

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  1. Yoon HJ and Carbon J (1999) Participation of Bir1p, a member of the inhibitor of apoptosis family, in yeast chromosome segregation events. Proc Natl Acad Sci U S A 96(23):13208-13 SGD PMID 10557299
  2. Li F, et al. (2000) Cell division regulation by BIR1, a member of the inhibitor of apoptosis family in yeast. J Biol Chem 275(10):6707-11 SGD PMID 10702224
  3. Makrantoni V and Stark MJ (2009) Efficient chromosome bi-orientation and the tension checkpoint in Saccharomyces cerevisiae both require Bir1. Mol Cell Biol SGD PMID 19528231
  4. Nakajima Y, et al. (2009) Nbl1p: a Borealin/Dasra/CSC-1-like protein essential for Aurora/Ipl1 complex function and integrity in Saccharomyces cerevisiae. Mol Biol Cell 20(6):1772-84 SGD PMID 19158380

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