Difference between revisions of "YJR060W"
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− | '''Description of YJR060W:''' Helix-loop-helix | + | '''Description of YJR060W:''' Helix-loop-helix trasnscription factor; binds the motif CACRTG which is present at several sites including MET gene promoters and centromere DNA element I (CDEI); required for nucleosome positioning at this motif; targets Isw1p to DNA; competes with Pho4p DNA binding motif and there by helps define the specificity of Pho4p gene regulation<ref name='S000059050'>Kent NA, et al. (2004) Cbf1p is required for chromatin remodeling at promoter-proximal CACGTG motifs in yeast. J Biol Chem 279(26):27116-23 {{SGDpaper|S000059050}} PMID 15111622</ref><ref name='S000073767'>Moreau JL, et al. (2003) Regulated displacement of TBP from the PHO8 promoter in vivo requires Cbf1 and the Isw1 chromatin remodeling complex. Mol Cell 11(6):1609-20 {{SGDpaper|S000073767}} PMID 12820973</ref><ref name='S000059647'>Wieland G, et al. (2001) Determination of the binding constants of the centromere protein Cbf1 to all 16 centromere DNAs of Saccharomyces cerevisiae. Nucleic Acids Res 29(5):1054-60 {{SGDpaper|S000059647}} PMID 11222754</ref><ref name='S000145916'>Zhou X and O'Shea EK (2011) Integrated Approaches Reveal Determinants of Genome-wide Binding and Function of the Transcription Factor Pho4. Mol Cell 42(6):826-36 |
− | {{SGDpaper| | + | {{SGDpaper|S000145916}} PMID 21700227</ref> |
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Revision as of 14:05, 28 July 2011
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Systematic name | YJR060W |
Gene name | CBF1 |
Aliases | CEP1, CPF1 |
Feature type | ORF, Verified |
Coordinates | Chr X:548759..549814 |
Primary SGDID | S000003821 |
Description of YJR060W: Helix-loop-helix trasnscription factor; binds the motif CACRTG which is present at several sites including MET gene promoters and centromere DNA element I (CDEI); required for nucleosome positioning at this motif; targets Isw1p to DNA; competes with Pho4p DNA binding motif and there by helps define the specificity of Pho4p gene regulation[1][2][3][4]
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References
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- ↑ Kent NA, et al. (2004) Cbf1p is required for chromatin remodeling at promoter-proximal CACGTG motifs in yeast. J Biol Chem 279(26):27116-23 SGD PMID 15111622
- ↑ Moreau JL, et al. (2003) Regulated displacement of TBP from the PHO8 promoter in vivo requires Cbf1 and the Isw1 chromatin remodeling complex. Mol Cell 11(6):1609-20 SGD PMID 12820973
- ↑ Wieland G, et al. (2001) Determination of the binding constants of the centromere protein Cbf1 to all 16 centromere DNAs of Saccharomyces cerevisiae. Nucleic Acids Res 29(5):1054-60 SGD PMID 11222754
- ↑ Zhou X and O'Shea EK (2011) Integrated Approaches Reveal Determinants of Genome-wide Binding and Function of the Transcription Factor Pho4. Mol Cell 42(6):826-36 SGD PMID 21700227
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