YJR047C

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Systematic name YJR047C
Gene name ANB1
Aliases HYP1, TIF51B
Feature type ORF, Verified
Coordinates Chr X:525374..524901
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Description of YJR047C: Translation initiation factor eIF-5A, promotes formation of the first peptide bond; similar to and functionally redundant with Hyp2p; undergoes an essential hypusination modification; expressed under anaerobic conditions[1][2][3]



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References

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  1. Schnier J, et al. (1991) Translation initiation factor 5A and its hypusine modification are essential for cell viability in the yeast Saccharomyces cerevisiae. Mol Cell Biol 11(6):3105-14 SGD PMID 1903841
  2. Kang HA, et al. (1993) Translation initiation factor eIF-5A, the hypusine-containing protein, is phosphorylated on serine in Saccharomyces cerevisiae. J Biol Chem 268(20):14750-6 SGD PMID 8325852
  3. Schwelberger HG, et al. (1993) Translation initiation factor eIF-5A expressed from either of two yeast genes or from human cDNA. Functional identity under aerobic and anaerobic conditions. J Biol Chem 268(19):14018-25 SGD PMID 8314769

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