YJR045C

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Systematic name YJR045C
Gene name SSC1
Aliases ENS1, mtHSP70
Feature type ORF, Verified
Coordinates Chr X:521594..519630
Primary SGDID S000003806


Description of YJR045C: Mitochondrial matrix ATPase, subunit of the presequence translocase-associated protein import motor (PAM) and of SceI endonuclease; involved in protein folding and translocation into the matrix; phosphorylated; member of HSP70 family[1][2][3][4][5]




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References

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  1. Reinders J, et al. (2007) Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase. Mol Cell Proteomics 6(11):1896-906 SGD PMID 17761666
  2. Liu Q, et al. (2001) Mitochondrial Hsp70 Ssc1: role in protein folding. J Biol Chem 276(9):6112-8 SGD PMID 11096111
  3. Truscott KN, et al. (2003) A J-protein is an essential subunit of the presequence translocase-associated protein import motor of mitochondria. J Cell Biol 163(4):707-13 SGD PMID 14638855
  4. Lopez-Buesa P, et al. (1998) The biochemical properties of the ATPase activity of a 70-kDa heat shock protein (Hsp70) are governed by the C-terminal domains. Proc Natl Acad Sci U S A 95(26):15253-8 SGD PMID 9860955
  5. Morishima N, et al. (1990) A subunit of yeast site-specific endonuclease SceI is a mitochondrial version of the 70-kDa heat shock protein. J Biol Chem 265(25):15189-97 SGD PMID 2203771

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