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Systematic name YJR045C
Gene name SSC1
Aliases ENS1, mtHSP70
Feature type ORF, Verified
Coordinates Chr X:521602..519638
Primary SGDID S000003806

Description of YJR045C: Hsp70 family ATPase, constituent of the import motor component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); involved in protein translocation and folding; subunit of SceI endonuclease[1][2][3][4]


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  1. Liu Q, et al. (2001) Mitochondrial Hsp70 Ssc1: role in protein folding. J Biol Chem 276(9):6112-8 SGD PMID 11096111
  2. Lopez-Buesa P, et al. (1998) The biochemical properties of the ATPase activity of a 70-kDa heat shock protein (Hsp70) are governed by the C-terminal domains. Proc Natl Acad Sci U S A 95(26):15253-8 SGD PMID 9860955
  3. Morishima N, et al. (1990) A subunit of yeast site-specific endonuclease SceI is a mitochondrial version of the 70-kDa heat shock protein. J Biol Chem 265(25):15189-97 SGD PMID 2203771
  4. Truscott KN, et al. (2003) A J-protein is an essential subunit of the presequence translocase-associated protein import motor of mitochondria. J Cell Biol 163(4):707-13 SGD PMID 14638855

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