Difference between revisions of "YJR024C"

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'''Description of YJR024C:''' Putative protein of unknown function; localizes to the cytoplasm; potential substrate of Smt3p sumoylation; expression downregulated by the antifungal drug caspofungin and deletion mutant exhibits enhanced caspofungin resistance<ref name='S000079733'>Panse VG, et al. (2004) A proteome-wide approach identifies sumoylated substrate proteins in yeast. J Biol Chem 279(40):41346-51 {{SGDpaper|S000079733}} PMID 15292183</ref><ref name='S000076477'>Lesage G, et al. (2004) Analysis of beta-1,3-glucan assembly in Saccharomyces cerevisiae using a synthetic interaction network and altered sensitivity to caspofungin. Genetics 167(1):35-49 {{SGDpaper|S000076477}} PMID 15166135</ref><ref name='S000075217'>Reinoso-Martin C, et al. (2003) The yeast protein kinase C cell integrity pathway mediates tolerance to the antifungal drug caspofungin through activation of Slt2p mitogen-activated protein kinase signaling. Eukaryot Cell 2(6):1200-10 {{SGDpaper|S000075217}} PMID 14665455</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91
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'''Description of YJR024C:''' Putative protein of unknown function with sequence similarity to methylthioribulose-1-phosphate dehydratases; potential Smt3p sumoylation substrate; expression downregulated by caspofungin and deletion mutant is caspofungin resistant<ref name='S000122946'>Sekowska A, et al. (2004) Bacterial variations on the methionine salvage pathway. BMC Microbiol 4():9 {{SGDpaper|S000122946}} PMID 15102328</ref><ref name='S000079733'>Panse VG, et al. (2004) A proteome-wide approach identifies sumoylated substrate proteins in yeast. J Biol Chem 279(40):41346-51 {{SGDpaper|S000079733}} PMID 15292183</ref><ref name='S000076477'>Lesage G, et al. (2004) Analysis of beta-1,3-glucan assembly in Saccharomyces cerevisiae using a synthetic interaction network and altered sensitivity to caspofungin. Genetics 167(1):35-49 {{SGDpaper|S000076477}} PMID 15166135</ref><ref name='S000075217'>Reinoso-Martin C, et al. (2003) The yeast protein kinase C cell integrity pathway mediates tolerance to the antifungal drug caspofungin through activation of Slt2p mitogen-activated protein kinase signaling. Eukaryot Cell 2(6):1200-10 {{SGDpaper|S000075217}} PMID 14665455</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91
 
  {{SGDpaper|S000074185}} PMID 14562095</ref>
 
  {{SGDpaper|S000074185}} PMID 14562095</ref>
 
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Revision as of 14:05, 12 June 2007

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Systematic name YJR024C
Gene name
Aliases
Feature type ORF, Uncharacterized
Coordinates Chr X:470957..470223
Primary SGDID S000003785


Description of YJR024C: Putative protein of unknown function with sequence similarity to methylthioribulose-1-phosphate dehydratases; potential Smt3p sumoylation substrate; expression downregulated by caspofungin and deletion mutant is caspofungin resistant[1][2][3][4][5]




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References

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  1. Sekowska A, et al. (2004) Bacterial variations on the methionine salvage pathway. BMC Microbiol 4():9 SGD PMID 15102328
  2. Panse VG, et al. (2004) A proteome-wide approach identifies sumoylated substrate proteins in yeast. J Biol Chem 279(40):41346-51 SGD PMID 15292183
  3. Lesage G, et al. (2004) Analysis of beta-1,3-glucan assembly in Saccharomyces cerevisiae using a synthetic interaction network and altered sensitivity to caspofungin. Genetics 167(1):35-49 SGD PMID 15166135
  4. Reinoso-Martin C, et al. (2003) The yeast protein kinase C cell integrity pathway mediates tolerance to the antifungal drug caspofungin through activation of Slt2p mitogen-activated protein kinase signaling. Eukaryot Cell 2(6):1200-10 SGD PMID 14665455
  5. Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095

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