YJR024C
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| Systematic name | YJR024C |
| Gene name | MDE1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr X:470964..470230 |
| Primary SGDID | S000003785 |
Description of YJR024C: 5'-methylthioribulose-1-phosphate dehydratase; acts in the methionine salvage pathway; potential Smt3p sumoylation substrate; expression downregulated by caspofungin and deletion mutant is caspofungin resistant[1][2][3][4][5]
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References
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- ↑ Lesage G, et al. (2004) Analysis of beta-1,3-glucan assembly in Saccharomyces cerevisiae using a synthetic interaction network and altered sensitivity to caspofungin. Genetics 167(1):35-49 SGD PMID 15166135
- ↑ Panse VG, et al. (2004) A proteome-wide approach identifies sumoylated substrate proteins in yeast. J Biol Chem 279(40):41346-51 SGD PMID 15292183
- ↑ Pirkov I, et al. (2008) A complete inventory of all enzymes in the eukaryotic methionine salvage pathway. FEBS J 275(16):4111-20 SGD PMID 18625006
- ↑ Reinoso-Martin C, et al. (2003) The yeast protein kinase C cell integrity pathway mediates tolerance to the antifungal drug caspofungin through activation of Slt2p mitogen-activated protein kinase signaling. Eukaryot Cell 2(6):1200-10 SGD PMID 14665455
- ↑ Sekowska A, et al. (2004) Bacterial variations on the methionine salvage pathway. BMC Microbiol 4():9 SGD PMID 15102328
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