Difference between revisions of "YJR024C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003785 YJR024C]  
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003785 YJR024C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||'' ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''MDE1 ''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||'' ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||'' ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
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|nowrap| Chr X:470957..470223
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|nowrap| Chr X:470956..470222
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003785
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003785
 
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'''Description of YJR024C:''' Putative protein of unknown function with sequence similarity to methylthioribulose-1-phosphate dehydratases; potential Smt3p sumoylation substrate; expression downregulated by caspofungin and deletion mutant is caspofungin resistant<ref name='S000122946'>Sekowska A, et al. (2004) Bacterial variations on the methionine salvage pathway. BMC Microbiol 4():9 {{SGDpaper|S000122946}} PMID 15102328</ref><ref name='S000079733'>Panse VG, et al. (2004) A proteome-wide approach identifies sumoylated substrate proteins in yeast. J Biol Chem 279(40):41346-51 {{SGDpaper|S000079733}} PMID 15292183</ref><ref name='S000076477'>Lesage G, et al. (2004) Analysis of beta-1,3-glucan assembly in Saccharomyces cerevisiae using a synthetic interaction network and altered sensitivity to caspofungin. Genetics 167(1):35-49 {{SGDpaper|S000076477}} PMID 15166135</ref><ref name='S000075217'>Reinoso-Martin C, et al. (2003) The yeast protein kinase C cell integrity pathway mediates tolerance to the antifungal drug caspofungin through activation of Slt2p mitogen-activated protein kinase signaling. Eukaryot Cell 2(6):1200-10 {{SGDpaper|S000075217}} PMID 14665455</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91
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'''Description of YJR024C:''' 5'-methylthioribulose-1-phosphate dehydratase; acts in the methionine salvage pathway; potential Smt3p sumoylation substrate; expression downregulated by caspofungin and deletion mutant is caspofungin resistant<ref name='S000127022'>Pirkov I, et al. (2008) A complete inventory of all enzymes in the eukaryotic methionine salvage pathway. FEBS J 275(16):4111-20 {{SGDpaper|S000127022}} PMID 18625006</ref><ref name='S000122946'>Sekowska A, et al. (2004) Bacterial variations on the methionine salvage pathway. BMC Microbiol 4:9 {{SGDpaper|S000122946}} PMID 15102328</ref><ref name='S000079733'>Panse VG, et al. (2004) A proteome-wide approach identifies sumoylated substrate proteins in yeast. J Biol Chem 279(40):41346-51 {{SGDpaper|S000079733}} PMID 15292183</ref><ref name='S000076477'>Lesage G, et al. (2004) Analysis of beta-1,3-glucan assembly in Saccharomyces cerevisiae using a synthetic interaction network and altered sensitivity to caspofungin. Genetics 167(1):35-49 {{SGDpaper|S000076477}} PMID 15166135</ref><ref name='S000075217'>Reinoso-Martin C, et al. (2003) The yeast protein kinase C cell integrity pathway mediates tolerance to the antifungal drug caspofungin through activation of Slt2p mitogen-activated protein kinase signaling. Eukaryot Cell 2(6):1200-10
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{{SGDpaper|S000074185}} PMID 14562095</ref>
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{{SGDpaper|S000075217}} PMID 14665455</ref>
 
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Revision as of 07:21, 26 February 2009

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Systematic name YJR024C
Gene name MDE1
Aliases
Feature type ORF, Uncharacterized
Coordinates Chr X:470956..470222
Primary SGDID S000003785


Description of YJR024C: 5'-methylthioribulose-1-phosphate dehydratase; acts in the methionine salvage pathway; potential Smt3p sumoylation substrate; expression downregulated by caspofungin and deletion mutant is caspofungin resistant[1][2][3][4][5]




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References

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  1. ↑ Pirkov I, et al. (2008) A complete inventory of all enzymes in the eukaryotic methionine salvage pathway. FEBS J 275(16):4111-20 SGD PMID 18625006
  2. ↑ Sekowska A, et al. (2004) Bacterial variations on the methionine salvage pathway. BMC Microbiol 4:9 SGD PMID 15102328
  3. ↑ Panse VG, et al. (2004) A proteome-wide approach identifies sumoylated substrate proteins in yeast. J Biol Chem 279(40):41346-51 SGD PMID 15292183
  4. ↑ Lesage G, et al. (2004) Analysis of beta-1,3-glucan assembly in Saccharomyces cerevisiae using a synthetic interaction network and altered sensitivity to caspofungin. Genetics 167(1):35-49 SGD PMID 15166135
  5. ↑ Reinoso-Martin C, et al. (2003) The yeast protein kinase C cell integrity pathway mediates tolerance to the antifungal drug caspofungin through activation of Slt2p mitogen-activated protein kinase signaling. Eukaryot Cell 2(6):1200-10 SGD PMID 14665455

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