Difference between revisions of "YJL210W"

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=== Protein Details ===
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[[Category:Topic:Protein Details]]
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==== Other Protein Details ====
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'''Other Topic''': Homology [[Category:Topic:Homology]]
  
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Homology was found, at the sequence and domain-composition level, between several components of the Peroxisomal protein import machinery and components of the Endoplasmic Reticulum Associated Decay (ERAD) pathway. This suggests a common evolutionary origin for both systems and a similar mechanism of action. The homology relationships can be stablished between Pex1,Pex6 and cdc48; Pex2 and Hrd1; Pex4 and Ubc1; and Pex5 and Hrd3. <ref name='S000114809'>Gabaldon T, et al. (2006) Origin and evolution of the peroxisomal proteome. Biol Direct 1():8 {{SGDpaper|S000114809}} PMID 16556314</ref> <ref name = 'CAset11335-2006-04-12'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=11335 Toni Gabaldon] on 2006-04-12</ref>
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==Community Commentary==
 
==Community Commentary==
 
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=== Protein Details ===
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[[Category:Topic:Protein Details]]
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==== Other Protein Details ====
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[[Category:Topic:Protein Details:Other Protein Details]]
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'''Other Topic''': Homology [[Category:Topic:Homology]]
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Homology was found, at the sequence and domain-composition level, between several components of the Peroxisomal protein import machinery and components of the Endoplasmic Reticulum Associated Decay (ERAD) pathway. This suggests a common evolutionary origin for both systems and a similar mechanism of action. The homology relationships can be stablished between Pex1,Pex6 and cdc48; Pex2 and Hrd1; Pex4 and Ubc1; and Pex5 and Hrd3. <ref name='S000114809'>Gabaldon T, et al. (2006) Origin and evolution of the peroxisomal proteome. Biol Direct 1():8 {{SGDpaper|S000114809}} PMID 16556314</ref> <ref name = 'CAset11335-2006-04-12'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=11335 Toni Gabaldon] on 2006-04-12</ref>
  
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==References==
 
==References==
 
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Revision as of 16:05, 23 January 2007

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Systematic name YJL210W
Gene name PEX2
Aliases CRT1, PAS5
Feature type ORF, Verified
Coordinates Chr X:36919..37734
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Description of YJL210W: RING-finger peroxin, peroxisomal membrane protein with a C-terminal zinc-binding RING domain, forms putative translocation subcomplex with Pex10p and Pex12p which functions in peroxisomal matrix protein import[1][2]



Protein Details

Other Protein Details

Other Topic: Homology

Homology was found, at the sequence and domain-composition level, between several components of the Peroxisomal protein import machinery and components of the Endoplasmic Reticulum Associated Decay (ERAD) pathway. This suggests a common evolutionary origin for both systems and a similar mechanism of action. The homology relationships can be stablished between Pex1,Pex6 and cdc48; Pex2 and Hrd1; Pex4 and Ubc1; and Pex5 and Hrd3. [3] [4]


Community Commentary

About Community Commentary. Please share your knowledge!

Protein Details

Other Protein Details

Other Topic: Homology

Homology was found, at the sequence and domain-composition level, between several components of the Peroxisomal protein import machinery and components of the Endoplasmic Reticulum Associated Decay (ERAD) pathway. This suggests a common evolutionary origin for both systems and a similar mechanism of action. The homology relationships can be stablished between Pex1,Pex6 and cdc48; Pex2 and Hrd1; Pex4 and Ubc1; and Pex5 and Hrd3. [3] [4]


References

See Help:References on how to add references

  1. Hazra PP, et al. (2002) Peroxisome remnants in pex3delta cells and the requirement of Pex3p for interactions between the peroxisomal docking and translocation subcomplexes. Traffic 3(8):560-74 SGD PMID 12121419
  2. Gould SJ and Valle D (2000) Peroxisome biogenesis disorders: genetics and cell biology. Trends Genet 16(8):340-5 SGD PMID 10904262
  3. 3.0 3.1 Gabaldon T, et al. (2006) Origin and evolution of the peroxisomal proteome. Biol Direct 1():8 SGD PMID 16556314
  4. 4.0 4.1 submitted by Toni Gabaldon on 2006-04-12

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