Difference between revisions of "YIR010W"
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+ | === Interactions === | ||
+ | [[Category:Topic:Interactions]] | ||
+ | ==== Genetic ==== | ||
+ | [[Category:Topic:Interactions:Genetic]] | ||
+ | YIR010W is a suppressor of MTW1 [[Category:Genetic Interaction with MTW1]] | ||
+ | |||
+ | '''Strain Background''': W303<br> | ||
+ | |||
+ | DSN1 is a high copy suppressor of the mtw1-1 mutant. <ref name='S000075182'>Pinsky BA, et al. (2003) An Mtw1 complex promotes kinetochore biorientation that is monitored by the Ipl1/Aurora protein kinase. Dev Cell 5(5):735-45 {{SGDpaper|S000075182}} PMID 14602074</ref> <ref name = 'CAset9883-2004-03-04'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9883 Benjamin Pinsky] on 2004-03-04</ref> | ||
+ | |||
+ | {{ShortCenteredHR}} | ||
+ | ==== Physical ==== | ||
+ | [[Category:Topic:Interactions:Physical]] | ||
+ | Physical interaction with NSL1 [[Category:Physical Interactions with NSL1]]<br> | ||
+ | Nsl1p co-immunoprecipitates Dsn1p. <ref name='S000075182'>Pinsky BA, et al. (2003) An Mtw1 complex promotes kinetochore biorientation that is monitored by the Ipl1/Aurora protein kinase. Dev Cell 5(5):735-45 {{SGDpaper|S000075182}} PMID 14602074</ref> <ref name = 'CAset9883-2004-03-04'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9883 Benjamin Pinsky] on 2004-03-04</ref> | ||
+ | |||
+ | {{ShortCenteredHR}} | ||
+ | Physical interaction with NNF1 [[Category:Physical Interactions with NNF1]]<br> | ||
+ | Nnf1p co-immunoprecipitates Dsn1p. <ref name='S000075182'>Pinsky BA, et al. (2003) An Mtw1 complex promotes kinetochore biorientation that is monitored by the Ipl1/Aurora protein kinase. Dev Cell 5(5):735-45 {{SGDpaper|S000075182}} PMID 14602074</ref> <ref name = 'CAset9883-2004-03-04'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9883 Benjamin Pinsky] on 2004-03-04</ref> | ||
+ | |||
+ | {{ShortCenteredHR}} | ||
+ | Physical interaction with MTW1 [[Category:Physical Interactions with MTW1]]<br> | ||
+ | Mtw1p co-immunoprecipitates Dsn1p. <ref name='S000075182'>Pinsky BA, et al. (2003) An Mtw1 complex promotes kinetochore biorientation that is monitored by the Ipl1/Aurora protein kinase. Dev Cell 5(5):735-45 {{SGDpaper|S000075182}} PMID 14602074</ref> <ref name = 'CAset9883-2004-03-04'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9883 Benjamin Pinsky] on 2004-03-04</ref> | ||
+ | |||
+ | {{ShortCenteredHR}} | ||
+ | Physical interaction with CSE4 [[Category:Physical Interactions with CSE4]]<br> | ||
+ | Cse4p co-immunopreciptates with Dsn1p. <ref name='S000075182'>Pinsky BA, et al. (2003) An Mtw1 complex promotes kinetochore biorientation that is monitored by the Ipl1/Aurora protein kinase. Dev Cell 5(5):735-45 {{SGDpaper|S000075182}} PMID 14602074</ref> <ref name = 'CAset9883-2004-03-04'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9883 Benjamin Pinsky] on 2004-03-04</ref> | ||
+ | |||
+ | {{ShortCenteredHR}} | ||
+ | Physical interaction with MIF2 [[Category:Physical Interactions with MIF2]]<br> | ||
+ | Mif2p co-immunoprecipitates Dsn1p. <ref name='S000075182'>Pinsky BA, et al. (2003) An Mtw1 complex promotes kinetochore biorientation that is monitored by the Ipl1/Aurora protein kinase. Dev Cell 5(5):735-45 {{SGDpaper|S000075182}} PMID 14602074</ref> <ref name = 'CAset9883-2004-03-04'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9883 Benjamin Pinsky] on 2004-03-04</ref> | ||
+ | |||
+ | {{ShortCenteredHR}} | ||
__TOC__ | __TOC__ | ||
==Community Commentary== | ==Community Commentary== | ||
{{CommentaryHelp}} | {{CommentaryHelp}} | ||
+ | === Interactions === | ||
+ | [[Category:Topic:Interactions]] | ||
+ | ==== Genetic ==== | ||
+ | [[Category:Topic:Interactions:Genetic]] | ||
+ | YIR010W is a suppressor of MTW1 [[Category:Genetic Interaction with MTW1]] | ||
+ | |||
+ | |||
+ | '''Strain Background''': W303<br> | ||
+ | |||
+ | DSN1 is a high copy suppressor of the mtw1-1 mutant. <ref name='S000075182'>Pinsky BA, et al. (2003) An Mtw1 complex promotes kinetochore biorientation that is monitored by the Ipl1/Aurora protein kinase. Dev Cell 5(5):735-45 {{SGDpaper|S000075182}} PMID 14602074</ref> <ref name = 'CAset9883-2004-03-04'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9883 Benjamin Pinsky] on 2004-03-04</ref> | ||
+ | |||
+ | {{ShortCenteredHR}} | ||
+ | ==== Physical ==== | ||
+ | [[Category:Topic:Interactions:Physical]] | ||
+ | Physical interaction with NSL1 [[Category:Physical Interactions with NSL1]]<br> | ||
+ | Nsl1p co-immunoprecipitates Dsn1p. <ref name='S000075182'>Pinsky BA, et al. (2003) An Mtw1 complex promotes kinetochore biorientation that is monitored by the Ipl1/Aurora protein kinase. Dev Cell 5(5):735-45 {{SGDpaper|S000075182}} PMID 14602074</ref> <ref name = 'CAset9883-2004-03-04'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9883 Benjamin Pinsky] on 2004-03-04</ref> | ||
+ | |||
+ | {{ShortCenteredHR}} | ||
+ | Physical interaction with NNF1 [[Category:Physical Interactions with NNF1]]<br> | ||
+ | Nnf1p co-immunoprecipitates Dsn1p. <ref name='S000075182'>Pinsky BA, et al. (2003) An Mtw1 complex promotes kinetochore biorientation that is monitored by the Ipl1/Aurora protein kinase. Dev Cell 5(5):735-45 {{SGDpaper|S000075182}} PMID 14602074</ref> <ref name = 'CAset9883-2004-03-04'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9883 Benjamin Pinsky] on 2004-03-04</ref> | ||
+ | |||
+ | {{ShortCenteredHR}} | ||
+ | Physical interaction with MTW1 [[Category:Physical Interactions with MTW1]]<br> | ||
+ | Mtw1p co-immunoprecipitates Dsn1p. <ref name='S000075182'>Pinsky BA, et al. (2003) An Mtw1 complex promotes kinetochore biorientation that is monitored by the Ipl1/Aurora protein kinase. Dev Cell 5(5):735-45 {{SGDpaper|S000075182}} PMID 14602074</ref> <ref name = 'CAset9883-2004-03-04'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9883 Benjamin Pinsky] on 2004-03-04</ref> | ||
+ | |||
+ | {{ShortCenteredHR}} | ||
+ | Physical interaction with CSE4 [[Category:Physical Interactions with CSE4]]<br> | ||
+ | Cse4p co-immunopreciptates with Dsn1p. <ref name='S000075182'>Pinsky BA, et al. (2003) An Mtw1 complex promotes kinetochore biorientation that is monitored by the Ipl1/Aurora protein kinase. Dev Cell 5(5):735-45 {{SGDpaper|S000075182}} PMID 14602074</ref> <ref name = 'CAset9883-2004-03-04'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9883 Benjamin Pinsky] on 2004-03-04</ref> | ||
+ | |||
+ | {{ShortCenteredHR}} | ||
+ | Physical interaction with MIF2 [[Category:Physical Interactions with MIF2]]<br> | ||
+ | Mif2p co-immunoprecipitates Dsn1p. <ref name='S000075182'>Pinsky BA, et al. (2003) An Mtw1 complex promotes kinetochore biorientation that is monitored by the Ipl1/Aurora protein kinase. Dev Cell 5(5):735-45 {{SGDpaper|S000075182}} PMID 14602074</ref> <ref name = 'CAset9883-2004-03-04'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9883 Benjamin Pinsky] on 2004-03-04</ref> | ||
+ | {{ShortCenteredHR}} | ||
==References== | ==References== | ||
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{{RefHelp}} | {{RefHelp}} |
Revision as of 17:05, 23 January 2007
Share your knowledge...Edit this entry!
Systematic name | YIR010W | |
Gene name | DSN1 | |
Aliases | ||
Feature type | ORF, Verified | |
Coordinates | Chr IX:375428..377158 | |
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Description of YIR010W: Essential component of the MIND kinetochore complex (Mtw1p Including Nnf1p-Nsl1p-Dsn1p) which joins kinetochore subunits contacting DNA to those contacting microtubules; important for chromosome segregation[1][2]
Interactions
Genetic
YIR010W is a suppressor of MTW1
Strain Background: W303
DSN1 is a high copy suppressor of the mtw1-1 mutant. [3] [4]
Physical
Physical interaction with NSL1
Nsl1p co-immunoprecipitates Dsn1p. [3] [4]
Physical interaction with NNF1
Nnf1p co-immunoprecipitates Dsn1p. [3] [4]
Physical interaction with MTW1
Mtw1p co-immunoprecipitates Dsn1p. [3] [4]
Physical interaction with CSE4
Cse4p co-immunopreciptates with Dsn1p. [3] [4]
Physical interaction with MIF2
Mif2p co-immunoprecipitates Dsn1p. [3] [4]
Contents
Community Commentary
About Community Commentary. Please share your knowledge!
Interactions
Genetic
YIR010W is a suppressor of MTW1
Strain Background: W303
DSN1 is a high copy suppressor of the mtw1-1 mutant. [3] [4]
Physical
Physical interaction with NSL1
Nsl1p co-immunoprecipitates Dsn1p. [3] [4]
Physical interaction with NNF1
Nnf1p co-immunoprecipitates Dsn1p. [3] [4]
Physical interaction with MTW1
Mtw1p co-immunoprecipitates Dsn1p. [3] [4]
Physical interaction with CSE4
Cse4p co-immunopreciptates with Dsn1p. [3] [4]
Physical interaction with MIF2
Mif2p co-immunoprecipitates Dsn1p. [3] [4]
References
See Help:References on how to add references
- ↑ De Wulf P, et al. (2003) Hierarchical assembly of the budding yeast kinetochore from multiple subcomplexes. Genes Dev 17(23):2902-21 SGD PMID 14633972
- ↑ Euskirchen GM (2002) Nnf1p, Dsn1p, Mtw1p, and Nsl1p: a new group of proteins important for chromosome segregation in Saccharomyces cerevisiae. Eukaryot Cell 1(2):229-40 SGD PMID 12455957
- ↑ 3.00 3.01 3.02 3.03 3.04 3.05 3.06 3.07 3.08 3.09 3.10 3.11 Pinsky BA, et al. (2003) An Mtw1 complex promotes kinetochore biorientation that is monitored by the Ipl1/Aurora protein kinase. Dev Cell 5(5):735-45 SGD PMID 14602074
- ↑ 4.00 4.01 4.02 4.03 4.04 4.05 4.06 4.07 4.08 4.09 4.10 4.11 submitted by Benjamin Pinsky on 2004-03-04
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