Difference between revisions of "YIR010W"

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=== Interactions ===
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[[Category:Topic:Interactions]]
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==== Genetic ====
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[[Category:Topic:Interactions:Genetic]]
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YIR010W is a suppressor of  MTW1 [[Category:Genetic Interaction with MTW1]]
  
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'''Strain Background''': W303<br>
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DSN1 is a high copy suppressor of the mtw1-1 mutant. <ref name='S000075182'>Pinsky BA, et al. (2003) An Mtw1 complex promotes kinetochore biorientation that is monitored by the Ipl1/Aurora protein kinase. Dev Cell 5(5):735-45 {{SGDpaper|S000075182}} PMID 14602074</ref> <ref name = 'CAset9883-2004-03-04'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9883 Benjamin Pinsky] on 2004-03-04</ref>
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{{ShortCenteredHR}}
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==== Physical ====
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[[Category:Topic:Interactions:Physical]]
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Physical interaction with NSL1 [[Category:Physical Interactions with NSL1]]<br>
 +
Nsl1p co-immunoprecipitates Dsn1p. <ref name='S000075182'>Pinsky BA, et al. (2003) An Mtw1 complex promotes kinetochore biorientation that is monitored by the Ipl1/Aurora protein kinase. Dev Cell 5(5):735-45 {{SGDpaper|S000075182}} PMID 14602074</ref> <ref name = 'CAset9883-2004-03-04'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9883 Benjamin Pinsky] on 2004-03-04</ref>
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{{ShortCenteredHR}}
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Physical interaction with NNF1 [[Category:Physical Interactions with NNF1]]<br>
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Nnf1p co-immunoprecipitates Dsn1p. <ref name='S000075182'>Pinsky BA, et al. (2003) An Mtw1 complex promotes kinetochore biorientation that is monitored by the Ipl1/Aurora protein kinase. Dev Cell 5(5):735-45 {{SGDpaper|S000075182}} PMID 14602074</ref> <ref name = 'CAset9883-2004-03-04'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9883 Benjamin Pinsky] on 2004-03-04</ref>
 +
 +
{{ShortCenteredHR}}
 +
Physical interaction with MTW1 [[Category:Physical Interactions with MTW1]]<br>
 +
Mtw1p co-immunoprecipitates Dsn1p. <ref name='S000075182'>Pinsky BA, et al. (2003) An Mtw1 complex promotes kinetochore biorientation that is monitored by the Ipl1/Aurora protein kinase. Dev Cell 5(5):735-45 {{SGDpaper|S000075182}} PMID 14602074</ref> <ref name = 'CAset9883-2004-03-04'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9883 Benjamin Pinsky] on 2004-03-04</ref>
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 +
{{ShortCenteredHR}}
 +
Physical interaction with CSE4 [[Category:Physical Interactions with CSE4]]<br>
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Cse4p co-immunopreciptates with Dsn1p. <ref name='S000075182'>Pinsky BA, et al. (2003) An Mtw1 complex promotes kinetochore biorientation that is monitored by the Ipl1/Aurora protein kinase. Dev Cell 5(5):735-45 {{SGDpaper|S000075182}} PMID 14602074</ref> <ref name = 'CAset9883-2004-03-04'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9883 Benjamin Pinsky] on 2004-03-04</ref>
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 +
{{ShortCenteredHR}}
 +
Physical interaction with MIF2 [[Category:Physical Interactions with MIF2]]<br>
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Mif2p co-immunoprecipitates Dsn1p. <ref name='S000075182'>Pinsky BA, et al. (2003) An Mtw1 complex promotes kinetochore biorientation that is monitored by the Ipl1/Aurora protein kinase. Dev Cell 5(5):735-45 {{SGDpaper|S000075182}} PMID 14602074</ref> <ref name = 'CAset9883-2004-03-04'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9883 Benjamin Pinsky] on 2004-03-04</ref>
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{{ShortCenteredHR}}
 
__TOC__
 
__TOC__
 
==Community Commentary==
 
==Community Commentary==
 
{{CommentaryHelp}}
 
{{CommentaryHelp}}
 +
=== Interactions ===
 +
[[Category:Topic:Interactions]]
 +
==== Genetic ====
 +
[[Category:Topic:Interactions:Genetic]]
 +
YIR010W is a suppressor of  MTW1 [[Category:Genetic Interaction with MTW1]]
 +
 +
 +
'''Strain Background''': W303<br>
 +
 +
DSN1 is a high copy suppressor of the mtw1-1 mutant. <ref name='S000075182'>Pinsky BA, et al. (2003) An Mtw1 complex promotes kinetochore biorientation that is monitored by the Ipl1/Aurora protein kinase. Dev Cell 5(5):735-45 {{SGDpaper|S000075182}} PMID 14602074</ref> <ref name = 'CAset9883-2004-03-04'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9883 Benjamin Pinsky] on 2004-03-04</ref>
 +
 +
{{ShortCenteredHR}}
 +
==== Physical ====
 +
[[Category:Topic:Interactions:Physical]]
 +
Physical interaction with NSL1 [[Category:Physical Interactions with NSL1]]<br>
 +
Nsl1p co-immunoprecipitates Dsn1p. <ref name='S000075182'>Pinsky BA, et al. (2003) An Mtw1 complex promotes kinetochore biorientation that is monitored by the Ipl1/Aurora protein kinase. Dev Cell 5(5):735-45 {{SGDpaper|S000075182}} PMID 14602074</ref> <ref name = 'CAset9883-2004-03-04'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9883 Benjamin Pinsky] on 2004-03-04</ref>
 +
 +
{{ShortCenteredHR}}
 +
Physical interaction with NNF1 [[Category:Physical Interactions with NNF1]]<br>
 +
Nnf1p co-immunoprecipitates Dsn1p. <ref name='S000075182'>Pinsky BA, et al. (2003) An Mtw1 complex promotes kinetochore biorientation that is monitored by the Ipl1/Aurora protein kinase. Dev Cell 5(5):735-45 {{SGDpaper|S000075182}} PMID 14602074</ref> <ref name = 'CAset9883-2004-03-04'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9883 Benjamin Pinsky] on 2004-03-04</ref>
 +
 +
{{ShortCenteredHR}}
 +
Physical interaction with MTW1 [[Category:Physical Interactions with MTW1]]<br>
 +
Mtw1p co-immunoprecipitates Dsn1p. <ref name='S000075182'>Pinsky BA, et al. (2003) An Mtw1 complex promotes kinetochore biorientation that is monitored by the Ipl1/Aurora protein kinase. Dev Cell 5(5):735-45 {{SGDpaper|S000075182}} PMID 14602074</ref> <ref name = 'CAset9883-2004-03-04'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9883 Benjamin Pinsky] on 2004-03-04</ref>
 +
 +
{{ShortCenteredHR}}
 +
Physical interaction with CSE4 [[Category:Physical Interactions with CSE4]]<br>
 +
Cse4p co-immunopreciptates with Dsn1p. <ref name='S000075182'>Pinsky BA, et al. (2003) An Mtw1 complex promotes kinetochore biorientation that is monitored by the Ipl1/Aurora protein kinase. Dev Cell 5(5):735-45 {{SGDpaper|S000075182}} PMID 14602074</ref> <ref name = 'CAset9883-2004-03-04'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9883 Benjamin Pinsky] on 2004-03-04</ref>
 +
 +
{{ShortCenteredHR}}
 +
Physical interaction with MIF2 [[Category:Physical Interactions with MIF2]]<br>
 +
Mif2p co-immunoprecipitates Dsn1p. <ref name='S000075182'>Pinsky BA, et al. (2003) An Mtw1 complex promotes kinetochore biorientation that is monitored by the Ipl1/Aurora protein kinase. Dev Cell 5(5):735-45 {{SGDpaper|S000075182}} PMID 14602074</ref> <ref name = 'CAset9883-2004-03-04'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9883 Benjamin Pinsky] on 2004-03-04</ref>
  
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{{ShortCenteredHR}}
 
==References==
 
==References==
 
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Revision as of 17:05, 23 January 2007

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Systematic name YIR010W
Gene name DSN1
Aliases
Feature type ORF, Verified
Coordinates Chr IX:375428..377158
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Description of YIR010W: Essential component of the MIND kinetochore complex (Mtw1p Including Nnf1p-Nsl1p-Dsn1p) which joins kinetochore subunits contacting DNA to those contacting microtubules; important for chromosome segregation[1][2]



Interactions

Genetic

YIR010W is a suppressor of MTW1


Strain Background: W303

DSN1 is a high copy suppressor of the mtw1-1 mutant. [3] [4]


Physical

Physical interaction with NSL1
Nsl1p co-immunoprecipitates Dsn1p. [3] [4]


Physical interaction with NNF1
Nnf1p co-immunoprecipitates Dsn1p. [3] [4]


Physical interaction with MTW1
Mtw1p co-immunoprecipitates Dsn1p. [3] [4]


Physical interaction with CSE4
Cse4p co-immunopreciptates with Dsn1p. [3] [4]


Physical interaction with MIF2
Mif2p co-immunoprecipitates Dsn1p. [3] [4]


Community Commentary

About Community Commentary. Please share your knowledge!

Interactions

Genetic

YIR010W is a suppressor of MTW1


Strain Background: W303

DSN1 is a high copy suppressor of the mtw1-1 mutant. [3] [4]


Physical

Physical interaction with NSL1
Nsl1p co-immunoprecipitates Dsn1p. [3] [4]


Physical interaction with NNF1
Nnf1p co-immunoprecipitates Dsn1p. [3] [4]


Physical interaction with MTW1
Mtw1p co-immunoprecipitates Dsn1p. [3] [4]


Physical interaction with CSE4
Cse4p co-immunopreciptates with Dsn1p. [3] [4]


Physical interaction with MIF2
Mif2p co-immunoprecipitates Dsn1p. [3] [4]


References

See Help:References on how to add references

  1. De Wulf P, et al. (2003) Hierarchical assembly of the budding yeast kinetochore from multiple subcomplexes. Genes Dev 17(23):2902-21 SGD PMID 14633972
  2. Euskirchen GM (2002) Nnf1p, Dsn1p, Mtw1p, and Nsl1p: a new group of proteins important for chromosome segregation in Saccharomyces cerevisiae. Eukaryot Cell 1(2):229-40 SGD PMID 12455957
  3. 3.00 3.01 3.02 3.03 3.04 3.05 3.06 3.07 3.08 3.09 3.10 3.11 Pinsky BA, et al. (2003) An Mtw1 complex promotes kinetochore biorientation that is monitored by the Ipl1/Aurora protein kinase. Dev Cell 5(5):735-45 SGD PMID 14602074
  4. 4.00 4.01 4.02 4.03 4.04 4.05 4.06 4.07 4.08 4.09 4.10 4.11 submitted by Benjamin Pinsky on 2004-03-04

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