Difference between revisions of "YIL066C"
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| − | '''Description of YIL066C:''' | + | '''Description of YIL066C:''' One of two large regulatory subunits of ribonucleotide-diphosphate reductase; the RNR complex catalyzes rate-limiting step in dNTP synthesis, regulated by DNA replication and DNA damage checkpoint pathways via localization of small subunits<ref name='S000073212'>Yao R, et al. (2003) Subcellular localization of yeast ribonucleotide reductase regulated by the DNA replication and damage checkpoint pathways. Proc Natl Acad Sci U S A 100(11):6628-33 {{SGDpaper|S000073212}} PMID 12732713</ref><ref name='S000046920'>Elledge SJ and Davis RW (1990) Two genes differentially regulated in the cell cycle and by DNA-damaging agents encode alternative regulatory subunits of ribonucleotide reductase. Genes Dev 4(5):740-51 |
| − | {{SGDpaper| | + | {{SGDpaper|S000046920}} PMID 2199320</ref> |
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Revision as of 14:05, 16 May 2008
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| Systematic name | YIL066C |
| Gene name | RNR3 |
| Aliases | DIN1, RIR3 |
| Feature type | ORF, Verified |
| Coordinates | Chr IX:240705..238096 |
| Primary SGDID | S000001328 |
Description of YIL066C: One of two large regulatory subunits of ribonucleotide-diphosphate reductase; the RNR complex catalyzes rate-limiting step in dNTP synthesis, regulated by DNA replication and DNA damage checkpoint pathways via localization of small subunits[1][2]
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References
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- ↑ Yao R, et al. (2003) Subcellular localization of yeast ribonucleotide reductase regulated by the DNA replication and damage checkpoint pathways. Proc Natl Acad Sci U S A 100(11):6628-33 SGD PMID 12732713
- ↑ Elledge SJ and Davis RW (1990) Two genes differentially regulated in the cell cycle and by DNA-damaging agents encode alternative regulatory subunits of ribonucleotide reductase. Genes Dev 4(5):740-51 SGD PMID 2199320
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