YIL066C
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| Systematic name | YIL066C |
| Gene name | RNR3 |
| Aliases | DIN1, RIR3 |
| Feature type | ORF, Verified |
| Coordinates | Chr IX:240708..238099 |
| Primary SGDID | S000001328 |
Description of YIL066C: Minor isoform of the large subunit of ribonucleotide-diphosphate reductase; the RNR complex catalyzes rate-limiting step in dNTP synthesis, regulated by DNA replication and DNA damage checkpoint pathways via localization of small subunits[1][2]
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References
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- ↑ Elledge SJ and Davis RW (1990) Two genes differentially regulated in the cell cycle and by DNA-damaging agents encode alternative regulatory subunits of ribonucleotide reductase. Genes Dev 4(5):740-51 SGD PMID 2199320
- ↑ Yao R, et al. (2003) Subcellular localization of yeast ribonucleotide reductase regulated by the DNA replication and damage checkpoint pathways. Proc Natl Acad Sci U S A 100(11):6628-33 SGD PMID 12732713
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