YHR216W
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| Systematic name | YHR216W | |
| Gene name | IMD2 | |
| Aliases | PUR5 | |
| Feature type | ORF, Verified | |
| Coordinates | Chr VIII:554396..555967 | |
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Description of YHR216W: Inosine monophosphate dehydrogenase, catalyzes the first step of GMP biosynthesis, expression is induced by mycophenolic acid resulting in resistance to the drug, expression is repressed by nutrient limitation[1][2]
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References
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- ↑ Escobar-Henriques M, et al. (2003) Transcription initiation of the yeast IMD2 gene is abolished in response to nutrient limitation through a sequence in its coding region. Mol Cell Biol 23(17):6279-90 SGD PMID 12917348
- ↑ Hyle JW, et al. (2003) Functional distinctions between IMP dehydrogenase genes in providing mycophenolate resistance and guanine prototrophy to yeast. J Biol Chem 278(31):28470-8 SGD PMID 12746440
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