Difference between revisions of "YHR200W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YHR200W YHR200W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001243 YHR200W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''RPN10 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''RPN10 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|nowrap| Chr VIII:499079..499885
 
|nowrap| Chr VIII:499079..499885
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000001243
 
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'''Description of {{PAGENAME}}:''' Non-ATPase base subunit of the 19S regulatory particle (RP) of the 26S proteasome; N-terminus plays a role in maintaining the structural integrity of the RP; binds selectively to polyubiquitin chains; homolog of the mammalian S5a protein<ref name='S000080888'>Deveraux Q, et al. (1994) A 26 S protease subunit that binds ubiquitin conjugates. J Biol Chem 269(10):7059-61 {{SGDpaper|S000080888}} PMID 8125911</ref><ref name='S000074998'>Elsasser S, et al. (2002) Proteasome subunit Rpn1 binds ubiquitin-like protein domains. Nat Cell Biol 4(9):725-30 {{SGDpaper|S000074998}} PMID 12198498</ref><ref name='S000058463'>Finley D, et al. (1998) Unified nomenclature for subunits of the Saccharomyces cerevisiae proteasome regulatory particle. Trends Biochem Sci 23(7):244-5 {{SGDpaper|S000058463}} PMID 9697412</ref><ref name='S000039974'>Glickman MH, et al. (1998) A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9-signalosome and eIF3. Cell 94(5):615-23
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'''Description of YHR200W:''' Non-ATPase base subunit of the 19S regulatory particle (RP) of the 26S proteasome; N-terminus plays a role in maintaining the structural integrity of the RP; binds selectively to polyubiquitin chains; homolog of the mammalian S5a protein<ref name='S000080888'>Deveraux Q, et al. (1994) A 26 S protease subunit that binds ubiquitin conjugates. J Biol Chem 269(10):7059-61 {{SGDpaper|S000080888}} PMID 8125911</ref><ref name='S000074998'>Elsasser S, et al. (2002) Proteasome subunit Rpn1 binds ubiquitin-like protein domains. Nat Cell Biol 4(9):725-30 {{SGDpaper|S000074998}} PMID 12198498</ref><ref name='S000058463'>Finley D, et al. (1998) Unified nomenclature for subunits of the Saccharomyces cerevisiae proteasome regulatory particle. Trends Biochem Sci 23(7):244-5 {{SGDpaper|S000058463}} PMID 9697412</ref><ref name='S000039974'>Glickman MH, et al. (1998) A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9-signalosome and eIF3. Cell 94(5):615-23
 
  {{SGDpaper|S000039974}} PMID 9741626</ref>
 
  {{SGDpaper|S000039974}} PMID 9741626</ref>
 
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J Biol Chem 278(5):3265-74</ref>
 
J Biol Chem 278(5):3265-74</ref>
 
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Revision as of 08:45, 27 February 2007

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Systematic name YHR200W
Gene name RPN10
Aliases MCB1, SUN1
Feature type ORF, Verified
Coordinates Chr VIII:499079..499885
Primary SGDID S000001243


Description of YHR200W: Non-ATPase base subunit of the 19S regulatory particle (RP) of the 26S proteasome; N-terminus plays a role in maintaining the structural integrity of the RP; binds selectively to polyubiquitin chains; homolog of the mammalian S5a protein[1][2][3][4]




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References

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  1. Deveraux Q, et al. (1994) A 26 S protease subunit that binds ubiquitin conjugates. J Biol Chem 269(10):7059-61 SGD PMID 8125911
  2. Elsasser S, et al. (2002) Proteasome subunit Rpn1 binds ubiquitin-like protein domains. Nat Cell Biol 4(9):725-30 SGD PMID 12198498
  3. Finley D, et al. (1998) Unified nomenclature for subunits of the Saccharomyces cerevisiae proteasome regulatory particle. Trends Biochem Sci 23(7):244-5 SGD PMID 9697412
  4. Glickman MH, et al. (1998) A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9-signalosome and eIF3. Cell 94(5):615-23 SGD PMID 9741626

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