YHR200W

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Systematic name YHR200W
Gene name RPN10
Aliases MCB1, SUN1
Feature type ORF, Verified
Coordinates Chr VIII:499079..499885
Primary SGDID S000001243


Description of YHR200W: Non-ATPase base subunit of the 19S regulatory particle (RP) of the 26S proteasome; N-terminus plays a role in maintaining the structural integrity of the RP; binds selectively to polyubiquitin chains; homolog of the mammalian S5a protein[1][2][3][4]




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References

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  1. Deveraux Q, et al. (1994) A 26 S protease subunit that binds ubiquitin conjugates. J Biol Chem 269(10):7059-61 SGD PMID 8125911
  2. Elsasser S, et al. (2002) Proteasome subunit Rpn1 binds ubiquitin-like protein domains. Nat Cell Biol 4(9):725-30 SGD PMID 12198498
  3. Finley D, et al. (1998) Unified nomenclature for subunits of the Saccharomyces cerevisiae proteasome regulatory particle. Trends Biochem Sci 23(7):244-5 SGD PMID 9697412
  4. Glickman MH, et al. (1998) A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9-signalosome and eIF3. Cell 94(5):615-23 SGD PMID 9741626

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