YHR187W
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| Systematic name | YHR187W |
| Gene name | IKI1 |
| Aliases | ELP5, HAP2, TOT5 |
| Feature type | ORF, Verified |
| Coordinates | Chr VIII:480990..481919 |
| Primary SGDID | S000001230 |
Description of YHR187W: Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; iki1 mutations confer resistance to the K. lactis toxin zymocin[1][2][3]
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References
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- ↑ Kishida M, et al. (1996) Isolation and genetic characterization of pGKL killer-insensitive mutants (iki) from Saccharomyces cerevisiae. Biosci Biotechnol Biochem 60(5):798-801 SGD PMID 8704309
- ↑ Frohloff F, et al. (2003) Subunit communications crucial for the functional integrity of the yeast RNA polymerase II elongator (gamma-toxin target (TOT)) complex. J Biol Chem 278(2):956-61 SGD PMID 12424236
- ↑ Esberg A, et al. (2006) Elevated levels of two tRNA species bypass the requirement for elongator complex in transcription and exocytosis. Mol Cell 24(1):139-48 SGD PMID 17018299
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