Difference between revisions of "YHR157W"
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| + | === Interactions === | ||
| + | [[Category:Topic:Interactions]] | ||
| + | ==== Physical ==== | ||
| + | [[Category:Topic:Interactions:Physical]] | ||
| + | Physical interaction with Rec102 [[Category:Physical Interactions with Rec102]]<br> | ||
| + | Immunoprecipitation and two-hybrid interactions. Both proteins are mutually interdependent for nuclear localization and association with meiotic chromosomes, and both also depend on Spo11p and Ski8p for chromatin association. <ref name='S000082211'>Kee K, et al. (2004) Spatial organization and dynamics of the association of Rec102 and Rec104 with meiotic chromosomes. EMBO J 23(8):1815-24 {{SGDpaper|S000082211}} PMID 15044957</ref> <ref name = 'CAset2960-2005-12-09'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=2960 Scott Keeney] on 2005-12-09</ref> | ||
| + | {{ShortCenteredHR}} | ||
| + | ==== Two Hybrid ==== | ||
| + | [[Category:Topic:Interactions:Two Hybrid]] | ||
| + | Two Hybrid interaction with Spo11 [[Category:Two Hybrid Interactions with Spo11]]<br> | ||
| + | meiosis-specific two hybrid interaction requires presence of endogenous SKI8 and REC102 genes <ref name='S000075846'>Arora C, et al. (2004) Antiviral protein Ski8 is a direct partner of Spo11 in meiotic DNA break formation, independent of its cytoplasmic role in RNA metabolism. Mol Cell 13(4):549-59 {{SGDpaper|S000075846}} PMID 14992724</ref> <ref name = 'CAset2960-2004-05-02'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=2960 Scott Keeney] on 2004-05-02</ref> | ||
| + | |||
| + | {{ShortCenteredHR}} | ||
| + | Two Hybrid interaction with Rec114 [[Category:Two Hybrid Interactions with Rec114]]<br> <ref name='S000075846'>Arora C, et al. (2004) Antiviral protein Ski8 is a direct partner of Spo11 in meiotic DNA break formation, independent of its cytoplasmic role in RNA metabolism. Mol Cell 13(4):549-59 {{SGDpaper|S000075846}} PMID 14992724</ref> <ref name = 'CAset2960-2004-05-02'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=2960 Scott Keeney] on 2004-05-02</ref> | ||
| + | |||
| + | {{ShortCenteredHR}} | ||
| + | === Protein Details === | ||
| + | [[Category:Topic:Protein Details]] | ||
| + | ==== Protein Localization ==== | ||
| + | [[Category:Topic:Protein Details:Protein Localization]] | ||
| + | |||
| + | Nuclear localization and association with meiotic chromosomes are dependent on Rec102p. Chromatin association ends abruptly during the pachytene stage of meiosis. <ref name='S000082211'>Kee K, et al. (2004) Spatial organization and dynamics of the association of Rec102 and Rec104 with meiotic chromosomes. EMBO J 23(8):1815-24 {{SGDpaper|S000082211}} PMID 15044957</ref> <ref name = 'CAset2960-2005-12-09'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=2960 Scott Keeney] on 2005-12-09</ref> | ||
| + | |||
| + | {{ShortCenteredHR}} | ||
| + | ==== Protein Modification ==== | ||
| + | [[Category:Topic:Protein Details:Protein Modification]] | ||
| + | '''Modification(s)''': Phosphorylation [[Category:Modification:Phosphorylation]] | ||
| + | |||
| + | Normal phosphorylation of Rec104p requires the presence of its protein interaction partner, Rec102p. <ref name='S000082211'>Kee K, et al. (2004) Spatial organization and dynamics of the association of Rec102 and Rec104 with meiotic chromosomes. EMBO J 23(8):1815-24 {{SGDpaper|S000082211}} PMID 15044957</ref> <ref name = 'CAset2960-2005-12-09'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=2960 Scott Keeney] on 2005-12-09</ref> | ||
| + | |||
| + | {{ShortCenteredHR}} | ||
__TOC__ | __TOC__ | ||
==Community Commentary== | ==Community Commentary== | ||
{{CommentaryHelp}} | {{CommentaryHelp}} | ||
| + | === Interactions === | ||
| + | [[Category:Topic:Interactions]] | ||
| + | ==== Physical ==== | ||
| + | [[Category:Topic:Interactions:Physical]] | ||
| + | Physical interaction with Rec102 [[Category:Physical Interactions with Rec102]]<br> | ||
| + | Immunoprecipitation and two-hybrid interactions. Both proteins are mutually interdependent for nuclear localization and association with meiotic chromosomes, and both also depend on Spo11p and Ski8p for chromatin association. <ref name='S000082211'>Kee K, et al. (2004) Spatial organization and dynamics of the association of Rec102 and Rec104 with meiotic chromosomes. EMBO J 23(8):1815-24 {{SGDpaper|S000082211}} PMID 15044957</ref> <ref name = 'CAset2960-2005-12-09'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=2960 Scott Keeney] on 2005-12-09</ref> | ||
| + | |||
| + | {{ShortCenteredHR}} | ||
| + | ==== Two Hybrid ==== | ||
| + | [[Category:Topic:Interactions:Two Hybrid]] | ||
| + | Two Hybrid interaction with Spo11 [[Category:Two Hybrid Interactions with Spo11]]<br> | ||
| + | meiosis-specific two hybrid interaction requires presence of endogenous SKI8 and REC102 genes <ref name='S000075846'>Arora C, et al. (2004) Antiviral protein Ski8 is a direct partner of Spo11 in meiotic DNA break formation, independent of its cytoplasmic role in RNA metabolism. Mol Cell 13(4):549-59 {{SGDpaper|S000075846}} PMID 14992724</ref> <ref name = 'CAset2960-2004-05-02'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=2960 Scott Keeney] on 2004-05-02</ref> | ||
| + | |||
| + | {{ShortCenteredHR}} | ||
| + | Two Hybrid interaction with Rec114 [[Category:Two Hybrid Interactions with Rec114]]<br> <ref name='S000075846'>Arora C, et al. (2004) Antiviral protein Ski8 is a direct partner of Spo11 in meiotic DNA break formation, independent of its cytoplasmic role in RNA metabolism. Mol Cell 13(4):549-59 {{SGDpaper|S000075846}} PMID 14992724</ref> <ref name = 'CAset2960-2004-05-02'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=2960 Scott Keeney] on 2004-05-02</ref> | ||
| + | |||
| + | {{ShortCenteredHR}} | ||
| + | === Protein Details === | ||
| + | [[Category:Topic:Protein Details]] | ||
| + | ==== Protein Localization ==== | ||
| + | [[Category:Topic:Protein Details:Protein Localization]] | ||
| + | |||
| + | Nuclear localization and association with meiotic chromosomes are dependent on Rec102p. Chromatin association ends abruptly during the pachytene stage of meiosis. <ref name='S000082211'>Kee K, et al. (2004) Spatial organization and dynamics of the association of Rec102 and Rec104 with meiotic chromosomes. EMBO J 23(8):1815-24 {{SGDpaper|S000082211}} PMID 15044957</ref> <ref name = 'CAset2960-2005-12-09'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=2960 Scott Keeney] on 2005-12-09</ref> | ||
| + | |||
| + | {{ShortCenteredHR}} | ||
| + | ==== Protein Modification ==== | ||
| + | [[Category:Topic:Protein Details:Protein Modification]] | ||
| + | '''Modification(s)''': Phosphorylation [[Category:Modification:Phosphorylation]] | ||
| + | |||
| + | Normal phosphorylation of Rec104p requires the presence of its protein interaction partner, Rec102p. <ref name='S000082211'>Kee K, et al. (2004) Spatial organization and dynamics of the association of Rec102 and Rec104 with meiotic chromosomes. EMBO J 23(8):1815-24 {{SGDpaper|S000082211}} PMID 15044957</ref> <ref name = 'CAset2960-2005-12-09'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=2960 Scott Keeney] on 2005-12-09</ref> | ||
| + | {{ShortCenteredHR}} | ||
==References== | ==References== | ||
<!-- REFERENCES ARE AUTOMATICALLY GENERATED. PLEASE DON'T EDIT THIS SECTION--> | <!-- REFERENCES ARE AUTOMATICALLY GENERATED. PLEASE DON'T EDIT THIS SECTION--> | ||
{{RefHelp}} | {{RefHelp}} | ||
Revision as of 17:05, 23 January 2007
Share your knowledge...Edit this entry!
| Systematic name | YHR157W | |
| Gene name | REC104 | |
| Aliases | ||
| Feature type | ORF, Verified | |
| Coordinates | Chr VIII:412910..413458 | |
| Don't edit this box! It's automatically regenerated, and edits will be lost when the update script runs. | ||
Description of YHR157W: Protein involved in early stages of meiotic recombination; required for meiotic crossing over; forms a complex with Rec102p and Spo11p necessary during the initiation of recombination[1][2][3]
Interactions
Physical
Physical interaction with Rec102
Immunoprecipitation and two-hybrid interactions. Both proteins are mutually interdependent for nuclear localization and association with meiotic chromosomes, and both also depend on Spo11p and Ski8p for chromatin association. [4] [5]
Two Hybrid
Two Hybrid interaction with Spo11
meiosis-specific two hybrid interaction requires presence of endogenous SKI8 and REC102 genes [6] [7]
Two Hybrid interaction with Rec114
[6] [7]
Protein Details
Protein Localization
Nuclear localization and association with meiotic chromosomes are dependent on Rec102p. Chromatin association ends abruptly during the pachytene stage of meiosis. [4] [5]
Protein Modification
Modification(s): Phosphorylation
Normal phosphorylation of Rec104p requires the presence of its protein interaction partner, Rec102p. [4] [5]
Contents
Community Commentary
About Community Commentary. Please share your knowledge!
Interactions
Physical
Physical interaction with Rec102
Immunoprecipitation and two-hybrid interactions. Both proteins are mutually interdependent for nuclear localization and association with meiotic chromosomes, and both also depend on Spo11p and Ski8p for chromatin association. [4] [5]
Two Hybrid
Two Hybrid interaction with Spo11
meiosis-specific two hybrid interaction requires presence of endogenous SKI8 and REC102 genes [6] [7]
Two Hybrid interaction with Rec114
[6] [7]
Protein Details
Protein Localization
Nuclear localization and association with meiotic chromosomes are dependent on Rec102p. Chromatin association ends abruptly during the pachytene stage of meiosis. [4] [5]
Protein Modification
Modification(s): Phosphorylation
Normal phosphorylation of Rec104p requires the presence of its protein interaction partner, Rec102p. [4] [5]
References
See Help:References on how to add references
- ↑ Jiao K, et al. (2003) Support for a meiotic recombination initiation complex: interactions among Rec102p, Rec104p, and Spo11p. Mol Cell Biol 23(16):5928-38 SGD PMID 12897161
- ↑ Malone RE, et al. (1991) Isolation of mutants defective in early steps of meiotic recombination in the yeast Saccharomyces cerevisiae. Genetics 128(1):79-88 SGD PMID 2060778
- ↑ Galbraith AM and Malone RE (1992) Characterization of REC104, a gene required for early meiotic recombination in the yeast Saccharomyces cerevisiae. Dev Genet 13(6):392-402 SGD PMID 1304422
- ↑ 4.0 4.1 4.2 4.3 4.4 4.5 Kee K, et al. (2004) Spatial organization and dynamics of the association of Rec102 and Rec104 with meiotic chromosomes. EMBO J 23(8):1815-24 SGD PMID 15044957
- ↑ 5.0 5.1 5.2 5.3 5.4 5.5 submitted by Scott Keeney on 2005-12-09
- ↑ 6.0 6.1 6.2 6.3 Arora C, et al. (2004) Antiviral protein Ski8 is a direct partner of Spo11 in meiotic DNA break formation, independent of its cytoplasmic role in RNA metabolism. Mol Cell 13(4):549-59 SGD PMID 14992724
- ↑ 7.0 7.1 7.2 7.3 submitted by Scott Keeney on 2004-05-02
See Help:Categories on how to add the wiki page for this gene to a Category
Categories:
- ORF
- ORF, Verified
- Topic:Interactions
- Topic:Interactions:Physical
- Physical Interactions with Rec102
- Topic:Interactions:Two Hybrid
- Two Hybrid Interactions with Spo11
- Two Hybrid Interactions with Rec114
- Topic:Protein Details
- Topic:Protein Details:Protein Localization
- Topic:Protein Details:Protein Modification
- Modification:Phosphorylation
