Difference between revisions of "YHR154W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YHR154W YHR154W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001197 YHR154W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''RTT107 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''RTT107 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|nowrap| Chr VIII:402969..406181
 
|nowrap| Chr VIII:402969..406181
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000001197
 
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'''Description of {{PAGENAME}}:''' Protein implicated in Mms22-dependent DNA repair during S phase, DNA damage induces phosphorylation by Mec1p at one or more SQ/TQ motifs; interacts with Mms22p and Slx4p; has four BRCT domains; has a role in regulation of Ty1 transposition<ref name='S000118873'>Roberts TM, et al. (2006) Slx4 regulates DNA damage checkpoint-dependent phosphorylation of the BRCT domain protein Rtt107/Esc4. Mol Biol Cell 17(1):539-48 {{SGDpaper|S000118873}} PMID 16267268</ref><ref name='S000079746'>Rouse J (2004) Esc4p, a new target of Mec1p (ATR), promotes resumption of DNA synthesis after DNA damage. EMBO J 23(5):1188-97 {{SGDpaper|S000079746}} PMID 14988729</ref><ref name='S000080900'>Baldwin EL, et al. (2005) Mms22p protects Saccharomyces cerevisiae from DNA damage induced by topoisomerase II. Nucleic Acids Res 33(3):1021-30 {{SGDpaper|S000080900}} PMID 15718301</ref><ref name='S000068874'>Scholes DT, et al. (2001) Multiple regulators of Ty1 transposition in Saccharomyces cerevisiae have conserved roles in genome maintenance. Genetics 159(4):1449-65
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'''Description of YHR154W:''' Protein implicated in Mms22-dependent DNA repair during S phase, DNA damage induces phosphorylation by Mec1p at one or more SQ/TQ motifs; interacts with Mms22p and Slx4p; has four BRCT domains; has a role in regulation of Ty1 transposition<ref name='S000118873'>Roberts TM, et al. (2006) Slx4 regulates DNA damage checkpoint-dependent phosphorylation of the BRCT domain protein Rtt107/Esc4. Mol Biol Cell 17(1):539-48 {{SGDpaper|S000118873}} PMID 16267268</ref><ref name='S000079746'>Rouse J (2004) Esc4p, a new target of Mec1p (ATR), promotes resumption of DNA synthesis after DNA damage. EMBO J 23(5):1188-97 {{SGDpaper|S000079746}} PMID 14988729</ref><ref name='S000080900'>Baldwin EL, et al. (2005) Mms22p protects Saccharomyces cerevisiae from DNA damage induced by topoisomerase II. Nucleic Acids Res 33(3):1021-30 {{SGDpaper|S000080900}} PMID 15718301</ref><ref name='S000068874'>Scholes DT, et al. (2001) Multiple regulators of Ty1 transposition in Saccharomyces cerevisiae have conserved roles in genome maintenance. Genetics 159(4):1449-65
 
  {{SGDpaper|S000068874}} PMID 11779788</ref>
 
  {{SGDpaper|S000068874}} PMID 11779788</ref>
 
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J Biol Chem 278(5):3265-74</ref>
 
J Biol Chem 278(5):3265-74</ref>
 
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Revision as of 08:45, 27 February 2007

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Systematic name YHR154W
Gene name RTT107
Aliases ESC4
Feature type ORF, Verified
Coordinates Chr VIII:402969..406181
Primary SGDID S000001197


Description of YHR154W: Protein implicated in Mms22-dependent DNA repair during S phase, DNA damage induces phosphorylation by Mec1p at one or more SQ/TQ motifs; interacts with Mms22p and Slx4p; has four BRCT domains; has a role in regulation of Ty1 transposition[1][2][3][4]




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References

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  1. Roberts TM, et al. (2006) Slx4 regulates DNA damage checkpoint-dependent phosphorylation of the BRCT domain protein Rtt107/Esc4. Mol Biol Cell 17(1):539-48 SGD PMID 16267268
  2. Rouse J (2004) Esc4p, a new target of Mec1p (ATR), promotes resumption of DNA synthesis after DNA damage. EMBO J 23(5):1188-97 SGD PMID 14988729
  3. Baldwin EL, et al. (2005) Mms22p protects Saccharomyces cerevisiae from DNA damage induced by topoisomerase II. Nucleic Acids Res 33(3):1021-30 SGD PMID 15718301
  4. Scholes DT, et al. (2001) Multiple regulators of Ty1 transposition in Saccharomyces cerevisiae have conserved roles in genome maintenance. Genetics 159(4):1449-65 SGD PMID 11779788

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