YHR090C

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Systematic name YHR090C
Gene name YNG2
Aliases EAF4, NBN1
Feature type ORF, Verified
Coordinates Chr VIII:284627..283779
Primary SGDID S000001132


Description of YHR090C: Subunit of the NuA4 histone acetyltransferase complex that acetylates histone H4 and H2A; has similarity to the human tumor suppressor ING1 and its isoforms ING4 and ING5[1][2][3]




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References

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  1. Gordon PM, et al. (2008) Interspecies data mining to predict novel ING-protein interactions in human. BMC Genomics 9:426 SGD PMID 18801192
  2. Loewith R, et al. (2000) Three yeast proteins related to the human candidate tumor suppressor p33(ING1) are associated with histone acetyltransferase activities. Mol Cell Biol 20(11):3807-16 SGD PMID 10805724
  3. Nourani A, et al. (2003) Opposite role of yeast ING family members in p53-dependent transcriptional activation. J Biol Chem 278(21):19171-5 SGD PMID 12672825

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