YHR090C
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| Systematic name | YHR090C |
| Gene name | YNG2 |
| Aliases | EAF4, NBN1 |
| Feature type | ORF, Verified |
| Coordinates | Chr VIII:284625..283777 |
| Primary SGDID | S000001132 |
Description of YHR090C: Subunit of NuA4, an essential histone acetyltransferase complex; positions Piccolo NuA4 for efficient acetylation of histone H4 or histone H2A; has similarity to the human tumor suppressor ING1 and its isoforms ING4 and ING5[1][2][3][4]
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References
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- ↑ Chittuluru JR, et al. (2011) Structure and nucleosome interaction of the yeast NuA4 and Piccolo-NuA4 histone acetyltransferase complexes.LID - 10.1038/nsmb.2128 [doi] Nat Struct Mol Biol () SGD PMID 21984211
- ↑ Gordon PM, et al. (2008) Interspecies data mining to predict novel ING-protein interactions in human. BMC Genomics 9:426 SGD PMID 18801192
- ↑ Loewith R, et al. (2000) Three yeast proteins related to the human candidate tumor suppressor p33(ING1) are associated with histone acetyltransferase activities. Mol Cell Biol 20(11):3807-16 SGD PMID 10805724
- ↑ Nourani A, et al. (2003) Opposite role of yeast ING family members in p53-dependent transcriptional activation. J Biol Chem 278(21):19171-5 SGD PMID 12672825
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