Difference between revisions of "YHR090C"

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'''Description of YHR090C:''' Subunit of the NuA4 histone acetyltransferase complex that acetylates histone H4 and H2A; has similarity to the human tumor suppressor ING1<ref name='S000073630'>Nourani A, et al. (2003) Opposite role of yeast ING family members in p53-dependent transcriptional activation. J Biol Chem 278(21):19171-5 {{SGDpaper|S000073630}} PMID 12672825</ref><ref name='S000043268'>Loewith R, et al. (2000) Three yeast proteins related to the human candidate tumor suppressor p33(ING1) are associated with histone acetyltransferase activities. Mol Cell Biol 20(11):3807-16
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'''Description of YHR090C:''' Subunit of the NuA4 histone acetyltransferase complex that acetylates histone H4 and H2A; has similarity to the human tumor suppressor ING1 and its isoforms ING4 and ING5<ref name='S000127778'>Gordon PM, et al. (2008) Interspecies data mining to predict novel ING-protein interactions in human. BMC Genomics 9(1):426 {{SGDpaper|S000127778}} PMID 18801192</ref><ref name='S000073630'>Nourani A, et al. (2003) Opposite role of yeast ING family members in p53-dependent transcriptional activation. J Biol Chem 278(21):19171-5 {{SGDpaper|S000073630}} PMID 12672825</ref><ref name='S000043268'>Loewith R, et al. (2000) Three yeast proteins related to the human candidate tumor suppressor p33(ING1) are associated with histone acetyltransferase activities. Mol Cell Biol 20(11):3807-16
 
  {{SGDpaper|S000043268}} PMID 10805724</ref>
 
  {{SGDpaper|S000043268}} PMID 10805724</ref>
 
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Revision as of 14:05, 2 October 2008

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Systematic name YHR090C
Gene name YNG2
Aliases EAF4, NBN1
Feature type ORF, Verified
Coordinates Chr VIII:284627..283779
Primary SGDID S000001132


Description of YHR090C: Subunit of the NuA4 histone acetyltransferase complex that acetylates histone H4 and H2A; has similarity to the human tumor suppressor ING1 and its isoforms ING4 and ING5[1][2][3]




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References

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  1. Gordon PM, et al. (2008) Interspecies data mining to predict novel ING-protein interactions in human. BMC Genomics 9(1):426 SGD PMID 18801192
  2. Nourani A, et al. (2003) Opposite role of yeast ING family members in p53-dependent transcriptional activation. J Biol Chem 278(21):19171-5 SGD PMID 12672825
  3. Loewith R, et al. (2000) Three yeast proteins related to the human candidate tumor suppressor p33(ING1) are associated with histone acetyltransferase activities. Mol Cell Biol 20(11):3807-16 SGD PMID 10805724

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