Difference between revisions of "YHR023W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YHR023W YHR023W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001065 YHR023W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''MYO1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''MYO1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|nowrap| Chr VIII:151659..157445
 
|nowrap| Chr VIII:151659..157445
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000001065
 
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'''Description of {{PAGENAME}}:''' Type II myosin heavy chain, required for wild-type cytokinesis and cell separation; localizes to the actomyosin ring; binds to myosin light chains Mlc1p and Mlc2p through its IQ1 and IQ2 motifs respectively<ref name='S000076268'>Luo J, et al. (2004) Identification and functional analysis of the essential and regulatory light chains of the only type II myosin Myo1p in Saccharomyces cerevisiae. J Cell Biol 165(6):843-55 {{SGDpaper|S000076268}} PMID 15210731</ref><ref name='S000072680'>Tolliday N, et al. (2003) Direct evidence for a critical role of myosin II in budding yeast cytokinesis and the evolvability of new cytokinetic mechanisms in the absence of myosin II. Mol Biol Cell 14(2):798-809 {{SGDpaper|S000072680}} PMID 12589071</ref><ref name='S000060912'>Brown SS (1997) Myosins in yeast. Curr Opin Cell Biol 9(1):44-8 {{SGDpaper|S000060912}} PMID 9013666</ref><ref name='S000053564'>Bi E, et al. (1998) Involvement of an actomyosin contractile ring in Saccharomyces cerevisiae cytokinesis. J Cell Biol 142(5):1301-12
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'''Description of YHR023W:''' Type II myosin heavy chain, required for wild-type cytokinesis and cell separation; localizes to the actomyosin ring; binds to myosin light chains Mlc1p and Mlc2p through its IQ1 and IQ2 motifs respectively<ref name='S000076268'>Luo J, et al. (2004) Identification and functional analysis of the essential and regulatory light chains of the only type II myosin Myo1p in Saccharomyces cerevisiae. J Cell Biol 165(6):843-55 {{SGDpaper|S000076268}} PMID 15210731</ref><ref name='S000072680'>Tolliday N, et al. (2003) Direct evidence for a critical role of myosin II in budding yeast cytokinesis and the evolvability of new cytokinetic mechanisms in the absence of myosin II. Mol Biol Cell 14(2):798-809 {{SGDpaper|S000072680}} PMID 12589071</ref><ref name='S000060912'>Brown SS (1997) Myosins in yeast. Curr Opin Cell Biol 9(1):44-8 {{SGDpaper|S000060912}} PMID 9013666</ref><ref name='S000053564'>Bi E, et al. (1998) Involvement of an actomyosin contractile ring in Saccharomyces cerevisiae cytokinesis. J Cell Biol 142(5):1301-12
 
  {{SGDpaper|S000053564}} PMID 9732290</ref>
 
  {{SGDpaper|S000053564}} PMID 9732290</ref>
 
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J Biol Chem 278(5):3265-74</ref>
 
J Biol Chem 278(5):3265-74</ref>
 
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Revision as of 08:45, 27 February 2007

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Systematic name YHR023W
Gene name MYO1
Aliases
Feature type ORF, Verified
Coordinates Chr VIII:151659..157445
Primary SGDID S000001065


Description of YHR023W: Type II myosin heavy chain, required for wild-type cytokinesis and cell separation; localizes to the actomyosin ring; binds to myosin light chains Mlc1p and Mlc2p through its IQ1 and IQ2 motifs respectively[1][2][3][4]




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Community Commentary

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Interactions

Genetic

Genetic interaction with hof1
Phenotype(s): Synthetic Lethal with hof1 Mutation type(s): deletion, deletion

[5] [6]




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References

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  1. Luo J, et al. (2004) Identification and functional analysis of the essential and regulatory light chains of the only type II myosin Myo1p in Saccharomyces cerevisiae. J Cell Biol 165(6):843-55 SGD PMID 15210731
  2. Tolliday N, et al. (2003) Direct evidence for a critical role of myosin II in budding yeast cytokinesis and the evolvability of new cytokinetic mechanisms in the absence of myosin II. Mol Biol Cell 14(2):798-809 SGD PMID 12589071
  3. Brown SS (1997) Myosins in yeast. Curr Opin Cell Biol 9(1):44-8 SGD PMID 9013666
  4. Bi E, et al. (1998) Involvement of an actomyosin contractile ring in Saccharomyces cerevisiae cytokinesis. J Cell Biol 142(5):1301-12 SGD PMID 9732290
  5. Vallen EA, et al. (2000) Roles of Hof1p, Bni1p, Bnr1p, and myo1p in cytokinesis in Saccharomyces cerevisiae. Mol Biol Cell 11(2):593-611 SGD PMID 10679017
  6. submitted by Erfei Bi on 2003-08-14

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