YHR023W
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| Systematic name | YHR023W |
| Gene name | MYO1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VIII:151666..157452 |
| Primary SGDID | S000001065 |
Description of YHR023W: Type II myosin heavy chain, required for wild-type cytokinesis and cell separation; localizes to the actomyosin ring; binds to myosin light chains Mlc1p and Mlc2p through its IQ1 and IQ2 motifs respectively[1][2][3][4]
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Community Commentary
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Interactions
Genetic
Genetic interaction with hof1
Phenotype(s): Synthetic Lethal with hof1
Mutation type(s): deletion, deletion
[5] [6]
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References
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- Jump up ↑ Bi E, et al. (1998) Involvement of an actomyosin contractile ring in Saccharomyces cerevisiae cytokinesis. J Cell Biol 142(5):1301-12 SGD PMID 9732290
- Jump up ↑ Brown SS (1997) Myosins in yeast. Curr Opin Cell Biol 9(1):44-8 SGD PMID 9013666
- Jump up ↑ Luo J, et al. (2004) Identification and functional analysis of the essential and regulatory light chains of the only type II myosin Myo1p in Saccharomyces cerevisiae. J Cell Biol 165(6):843-55 SGD PMID 15210731
- Jump up ↑ Tolliday N, et al. (2003) Direct evidence for a critical role of myosin II in budding yeast cytokinesis and the evolvability of new cytokinetic mechanisms in the absence of myosin II. Mol Biol Cell 14(2):798-809 SGD PMID 12589071
- Jump up ↑ Vallen EA, et al. (2000) Roles of Hof1p, Bni1p, Bnr1p, and myo1p in cytokinesis in Saccharomyces cerevisiae. Mol Biol Cell 11(2):593-611 SGD PMID 10679017
- Jump up ↑ submitted by Erfei Bi on 2003-08-14
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