YGR185C

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Systematic name YGR185C
Gene name TYS1
Aliases TTS1, TyrRS
Feature type ORF, Verified
Coordinates Chr VII:867525..866341
Primary SGDID S000003417


Description of YGR185C: Cytoplasmic tyrosyl-tRNA synthetase, class I aminoacyl-tRNA synthetase that aminoacylates tRNA(Tyr), required for cytoplasmic protein synthesis, interacts with positions 34 and 35 of the anticodon of tRNATyr[1][2][3][4]




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References

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  1. Bare LA and Uhlenbeck OC (1986) Specific substitution into the anticodon loop of yeast tyrosine transfer RNA. Biochemistry 25(19):5825-30 SGD PMID 3535890
  2. Chow CM and RajBhandary UL (1993) Saccharomyces cerevisiae cytoplasmic tyrosyl-tRNA synthetase gene. Isolation by complementation of a mutant Escherichia coli suppressor tRNA defective in aminoacylation and sequence analysis. J Biol Chem 268(17):12855-63 SGD PMID 8509419
  3. Cavarelli J, et al. (1993) Yeast tRNA(Asp) recognition by its cognate class II aminoacyl-tRNA synthetase. Nature 362(6416):181-4 SGD PMID 8450889
  4. Guan MX (1997) Cytoplasmic tyrosyl-tRNA synthetase rescues the defect in mitochondrial genome maintenance caused by the nuclear mutation mgm104-1 in the yeast Saccharomyces cerevisiae. Mol Gen Genet 255(5):525-32 SGD PMID 9294037

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