Difference between revisions of "YGR033C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003265 YGR033C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003265 YGR033C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''TIM21 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''TIM21 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr VII:554971..554252
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|nowrap| Chr VII:554967..554248
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003265
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003265
 
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'''Description of YGR033C:''' Nonessential subunit of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); interacts with the Translocase of the Outer Mitochondrial membrane (TOM complex) and with respiratory enzymes; may regulate TIM23 complex activity<ref name='S000081217'>Chacinska A, et al. (2005) Mitochondrial presequence translocase: switching between TOM tethering and motor recruitment involves Tim21 and Tim17. Cell 120(6):817-29 {{SGDpaper|S000081217}} PMID 15797382</ref><ref name='S000122547'>Mokranjac D, et al. (2005) Role of Tim21 in mitochondrial translocation contact sites. J Biol Chem 280(25):23437-40 {{SGDpaper|S000122547}} PMID 15878866</ref><ref name='S000123629'>van der Laan M, et al. (2006) A role for Tim21 in membrane-potential-dependent preprotein sorting in mitochondria. Curr Biol 16(22):2271-6 {{SGDpaper|S000123629}} PMID 17113393</ref><ref name='S000129493'>Popov-Celeketic D, et al. (2008) Active remodelling of the TIM23 complex during translocation of preproteins into mitochondria. EMBO J 27(10):1469-80
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'''Description of YGR033C:''' Nonessential subunit of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); interacts with the Translocase of the Outer Mitochondrial membrane (TOM complex) and with respiratory enzymes; may regulate TIM23 complex activity<ref name='S000081217'>Chacinska A, et al. (2005) Mitochondrial presequence translocase: switching between TOM tethering and motor recruitment involves Tim21 and Tim17. Cell 120(6):817-29 {{SGDpaper|S000081217}} PMID 15797382</ref><ref name='S000122547'>Mokranjac D, et al. (2005) Role of Tim21 in mitochondrial translocation contact sites. J Biol Chem 280(25):23437-40 {{SGDpaper|S000122547}} PMID 15878866</ref><ref name='S000129493'>Popov-Celeketic D, et al. (2008) Active remodelling of the TIM23 complex during translocation of preproteins into mitochondria. EMBO J 27(10):1469-80 {{SGDpaper|S000129493}} PMID 18418384</ref><ref name='S000123629'>van der Laan M, et al. (2006) A role for Tim21 in membrane-potential-dependent preprotein sorting in mitochondria. Curr Biol 16(22):2271-6
  {{SGDpaper|S000129493}} PMID 18418384</ref>
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  {{SGDpaper|S000123629}} PMID 17113393</ref>
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YGR033C
Gene name TIM21
Aliases FMP17
Feature type ORF, Verified
Coordinates Chr VII:554967..554248
Primary SGDID S000003265


Description of YGR033C: Nonessential subunit of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); interacts with the Translocase of the Outer Mitochondrial membrane (TOM complex) and with respiratory enzymes; may regulate TIM23 complex activity[1][2][3][4]




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References

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  1. Chacinska A, et al. (2005) Mitochondrial presequence translocase: switching between TOM tethering and motor recruitment involves Tim21 and Tim17. Cell 120(6):817-29 SGD PMID 15797382
  2. Mokranjac D, et al. (2005) Role of Tim21 in mitochondrial translocation contact sites. J Biol Chem 280(25):23437-40 SGD PMID 15878866
  3. Popov-Celeketic D, et al. (2008) Active remodelling of the TIM23 complex during translocation of preproteins into mitochondria. EMBO J 27(10):1469-80 SGD PMID 18418384
  4. van der Laan M, et al. (2006) A role for Tim21 in membrane-potential-dependent preprotein sorting in mitochondria. Curr Biol 16(22):2271-6 SGD PMID 17113393

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