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Systematic name YGR033C
Gene name TIM21
Aliases FMP17
Feature type ORF, Verified
Coordinates Chr VII:554967..554248
Primary SGDID S000003265

Description of YGR033C: Nonessential subunit of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); interacts with the Translocase of the Outer Mitochondrial membrane (TOM complex) and with respiratory enzymes; may regulate TIM23 complex activity[1][2][3][4]


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  1. Chacinska A, et al. (2005) Mitochondrial presequence translocase: switching between TOM tethering and motor recruitment involves Tim21 and Tim17. Cell 120(6):817-29 SGD PMID 15797382
  2. Mokranjac D, et al. (2005) Role of Tim21 in mitochondrial translocation contact sites. J Biol Chem 280(25):23437-40 SGD PMID 15878866
  3. Popov-Celeketic D, et al. (2008) Active remodelling of the TIM23 complex during translocation of preproteins into mitochondria. EMBO J 27(10):1469-80 SGD PMID 18418384
  4. van der Laan M, et al. (2006) A role for Tim21 in membrane-potential-dependent preprotein sorting in mitochondria. Curr Biol 16(22):2271-6 SGD PMID 17113393

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