Difference between revisions of "YGR033C"
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| − | '''Description of YGR033C:''' | + | '''Description of YGR033C:''' Nonessential subunit of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); interacts with the Translocase of the Outer Mitochondrial membrane (TOM complex) and with respiratory enzymes; may regulate TIM23 complex activity<ref name='S000081217'>Chacinska A, et al. (2005) Mitochondrial presequence translocase: switching between TOM tethering and motor recruitment involves Tim21 and Tim17. Cell 120(6):817-29 {{SGDpaper|S000081217}} PMID 15797382</ref><ref name='S000122547'>Mokranjac D, et al. (2005) Role of Tim21 in mitochondrial translocation contact sites. J Biol Chem 280(25):23437-40 {{SGDpaper|S000122547}} PMID 15878866</ref><ref name='S000123629'>van der Laan M, et al. (2006) A role for Tim21 in membrane-potential-dependent preprotein sorting in mitochondria. Curr Biol 16(22):2271-6 {{SGDpaper|S000123629}} PMID 17113393</ref><ref name='S000129493'>Popov-Celeketic D, et al. (2008) Active remodelling of the TIM23 complex during translocation of preproteins into mitochondria. EMBO J 27(10):1469-80 |
| − | {{SGDpaper| | + | {{SGDpaper|S000129493}} PMID 18418384</ref> |
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Revision as of 14:05, 4 August 2009
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| Systematic name | YGR033C |
| Gene name | TIM21 |
| Aliases | FMP17 |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:554971..554252 |
| Primary SGDID | S000003265 |
Description of YGR033C: Nonessential subunit of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); interacts with the Translocase of the Outer Mitochondrial membrane (TOM complex) and with respiratory enzymes; may regulate TIM23 complex activity[1][2][3][4]
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References
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- ↑ Chacinska A, et al. (2005) Mitochondrial presequence translocase: switching between TOM tethering and motor recruitment involves Tim21 and Tim17. Cell 120(6):817-29 SGD PMID 15797382
- ↑ Mokranjac D, et al. (2005) Role of Tim21 in mitochondrial translocation contact sites. J Biol Chem 280(25):23437-40 SGD PMID 15878866
- ↑ van der Laan M, et al. (2006) A role for Tim21 in membrane-potential-dependent preprotein sorting in mitochondria. Curr Biol 16(22):2271-6 SGD PMID 17113393
- ↑ Popov-Celeketic D, et al. (2008) Active remodelling of the TIM23 complex during translocation of preproteins into mitochondria. EMBO J 27(10):1469-80 SGD PMID 18418384
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