Difference between revisions of "YGL213C"
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Revision as of 08:17, 30 January 2007
Share your knowledge...Edit this entry! <protect>
| Systematic name | YGL213C |
| Gene name | SKI8 |
| Aliases | REC103 |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:91251..90058 |
Description of YGL213C: Protein involved in exosome mediated 3' to 5' mRNA degradation and translation inhibition of non-poly(A) mRNAs as well as double-strand break formation during meiotic recombination; required for repressing propagation of dsRNA viruses[1][2][3][4]
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Contents
Community Commentary
About Community Commentary. Please share your knowledge!
Interactions
Two Hybrid
Two Hybrid interaction with spo11
[1] [5]
Protein Details
Protein Localization
cytoplasmic localization during vegetative growth, relocalizes to nucleus and onto chromosomes during meiosis [1] [5]
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References
See Help:References on how to add references
- ↑ 1.0 1.1 1.2 Arora C, et al. (2004) Antiviral protein Ski8 is a direct partner of Spo11 in meiotic DNA break formation, independent of its cytoplasmic role in RNA metabolism. Mol Cell 13(4):549-59 SGD PMID 14992724
- ↑ Anderson JS and Parker RP (1998) The 3' to 5' degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3' to 5' exonucleases of the exosome complex. EMBO J 17(5):1497-506 SGD PMID 9482746
- ↑ Masison DC, et al. (1995) Decoying the cap- mRNA degradation system by a double-stranded RNA virus and poly(A)- mRNA surveillance by a yeast antiviral system. Mol Cell Biol 15(5):2763-71 SGD PMID 7739557
- ↑ Brown JT, et al. (2000) The yeast antiviral proteins Ski2p, Ski3p, and Ski8p exist as a complex in vivo. RNA 6(3):449-57 SGD PMID 10744028
- ↑ 5.0 5.1 submitted by Scott Keeney on 2004-05-02
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