Difference between revisions of "YGL213C"

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=== Interactions ===
 
[[Category:Topic:Interactions]]
 
==== Two Hybrid ====
 
[[Category:Topic:Interactions:Two Hybrid]]
 
Two Hybrid interaction with spo11 [[Category:Two Hybrid Interactions with spo11]]<br> <ref name='S000075846'>Arora C, et al. (2004) Antiviral protein Ski8 is a direct partner of Spo11 in meiotic DNA break formation, independent of its cytoplasmic role in RNA metabolism. Mol Cell 13(4):549-59 {{SGDpaper|S000075846}} PMID 14992724</ref> <ref name = 'CAset2960-2004-05-02'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=2960 Scott Keeney] on 2004-05-02</ref>
 
 
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=== Protein Details ===
 
[[Category:Topic:Protein Details]]
 
==== Protein Localization ====
 
[[Category:Topic:Protein Details:Protein Localization]]
 
 
cytoplasmic localization during vegetative growth, relocalizes to nucleus and onto chromosomes during meiosis <ref name='S000075846'>Arora C, et al. (2004) Antiviral protein Ski8 is a direct partner of Spo11 in meiotic DNA break formation, independent of its cytoplasmic role in RNA metabolism. Mol Cell 13(4):549-59 {{SGDpaper|S000075846}} PMID 14992724</ref> <ref name = 'CAset2960-2004-05-02'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=2960 Scott Keeney] on 2004-05-02</ref>
 
 
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==Community Commentary==
 
==Community Commentary==

Revision as of 11:51, 24 January 2007

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Systematic name YGL213C
Gene name SKI8
Aliases REC103
Feature type ORF, Verified
Coordinates Chr VII:91251..90058
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Description of YGL213C: Protein involved in exosome mediated 3' to 5' mRNA degradation and translation inhibition of non-poly(A) mRNAs as well as double-strand break formation during meiotic recombination; required for repressing propagation of dsRNA viruses[1][2][3][4]



Community Commentary

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Interactions

Two Hybrid

Two Hybrid interaction with spo11
[1] [5]


Protein Details

Protein Localization

cytoplasmic localization during vegetative growth, relocalizes to nucleus and onto chromosomes during meiosis [1] [5]


References

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  1. 1.0 1.1 1.2 Arora C, et al. (2004) Antiviral protein Ski8 is a direct partner of Spo11 in meiotic DNA break formation, independent of its cytoplasmic role in RNA metabolism. Mol Cell 13(4):549-59 SGD PMID 14992724
  2. Anderson JS and Parker RP (1998) The 3' to 5' degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3' to 5' exonucleases of the exosome complex. EMBO J 17(5):1497-506 SGD PMID 9482746
  3. Masison DC, et al. (1995) Decoying the cap- mRNA degradation system by a double-stranded RNA virus and poly(A)- mRNA surveillance by a yeast antiviral system. Mol Cell Biol 15(5):2763-71 SGD PMID 7739557
  4. Brown JT, et al. (2000) The yeast antiviral proteins Ski2p, Ski3p, and Ski8p exist as a complex in vivo. RNA 6(3):449-57 SGD PMID 10744028
  5. 5.0 5.1 submitted by Scott Keeney on 2004-05-02

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