Difference between revisions of "YGL209W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003177 YGL209W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MIG2 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''MIG2 '' | ||
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| − | '''Description of YGL209W:''' | + | '''Description of YGL209W:''' Zinc finger transcriptional repressor; cooperates with Mig1p in glucose-induced repression of many genes including SUC2 (invertase); binds to Mig1p-binding sites in SUC2 promoter; under low glucose conditions Mig2p relocalizes to mitochondrion, where it regulates morphology, interacts with Ups1p and antagonizes mitochondrial fission factor, Dnm1p, indicative of a role in promoting mitochondrial fusion or regulating morphology<ref name='S000148467'>Fernandez-Cid A, et al. (2012) Glucose levels regulate the nucleo-mitochondrial distribution of Mig2. Mitochondrion () {{SGDpaper|S000148467}} PMID 22353369</ref><ref name='S000043442'>Lutfiyya LL and Johnston M (1996) Two zinc-finger-containing repressors are responsible for glucose repression of SUC2 expression. Mol Cell Biol 16(9):4790-7 |
{{SGDpaper|S000043442}} PMID 8756637</ref> | {{SGDpaper|S000043442}} PMID 8756637</ref> | ||
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Latest revision as of 14:05, 5 April 2012
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| Systematic name | YGL209W |
| Gene name | MIG2 |
| Aliases | MLZ1 |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:95858..97006 |
| Primary SGDID | S000003177 |
Description of YGL209W: Zinc finger transcriptional repressor; cooperates with Mig1p in glucose-induced repression of many genes including SUC2 (invertase); binds to Mig1p-binding sites in SUC2 promoter; under low glucose conditions Mig2p relocalizes to mitochondrion, where it regulates morphology, interacts with Ups1p and antagonizes mitochondrial fission factor, Dnm1p, indicative of a role in promoting mitochondrial fusion or regulating morphology[1][2]
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Contents
Community Commentary
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DNA and RNA Details
Other DNA and RNA Details
Other Topic: expression
Specifically lower expression in carbon limited chemostat cultures versus carbon excess. [3] [4]
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References
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- ↑ Fernandez-Cid A, et al. (2012) Glucose levels regulate the nucleo-mitochondrial distribution of Mig2. Mitochondrion () SGD PMID 22353369
- ↑ Lutfiyya LL and Johnston M (1996) Two zinc-finger-containing repressors are responsible for glucose repression of SUC2 expression. Mol Cell Biol 16(9):4790-7 SGD PMID 8756637
- ↑ Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
- ↑ submitted by Viktor Boer on 2003-07-25
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